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dati in vitro, ex-vivo e in modelli animali suggeriscono che bortezomib incrementi la differenziazione e l’attività osteoblastica e inibisca la funzione osteoclastica.
data from in vitro, ex-vivo, and animal models with bortezomib suggest that it increases osteoblast differentiation and activity and inhibits osteoclast function.