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Lithuanian

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· padidjusios kepenys ar bluznis.

· hepatomegaly or splenomegaly

Last Update: 2012-02-08
Subject: Medical
Usage Frequency: 1
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-jeigu Jus sergate Kaposi sarkoma ir Jums pasalinta bluznis.

-if you have Kaposi 's sarcoma and have had your spleen removed.

Last Update: 2013-09-27
Subject: Medical
Usage Frequency: 1
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Del to gali padidti kepenys ir bluznis, atsirasti pakitimu kraujyje bei kaulu pazeidimu.

This can result in liver and spleen enlargement, changes in the blood, and affect the bones

Last Update: 2013-09-27
Subject: Medical
Usage Frequency: 1
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Dl sios ligos gali padidti limfiniai mazgai ir kiti organai, pvz., kepenys ir bluznis.

The illness may also cause the lymph nodes and other organs such as liver and spleen to enlarge.

Last Update: 2013-09-27
Subject: Medical
Usage Frequency: 1
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Inkstai Kepenys Slapimo pusle Kiausides Gimda Bluznis Kaulai Sirdis Plauciai Zarnynas Raumenys Sklids

Kidneys Liver Bladder Ovaries Uterus Spleen Bones Heart Lungs Intestines Muscles Testes

Last Update: 2013-09-27
Subject: Medical
Usage Frequency: 1
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Padidejusi bluznis su histiocitoze stebeta ziurkems, bet sie pokyciai nebuvo rasti kitiems gyvunams.

Enlarged spleens with histiocytosis were observed in rats but these changes weren't found in other species.

Last Update: 2013-09-27
Subject: Medical
Usage Frequency: 3
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Organas taikinys Inkstai Bluznis Sklids Skydliauk Kaul ciulpai Kepenys Kaul pavirsiai Sirdies sienel Plauciai Antinksciai Kasa Slapimo psl Gimda Plonzarn Virsutin storzarn Kiausids Apatin storzarn

Target Organ Kidneys Spleen Testes Thyroid gland Bone marrow Liver Bone surface Heart wall Lungs Adrenal glands Pancreas Urinary bladder Uterus Small intestine Upper large intestine Ovaries Lower large intestine

Last Update: 2008-03-04
Subject: Medical
Usage Frequency: 1
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Kartotini dozi toksiskumo grauzikams ir sunims tyrimais nustatyta, kad pagrindiniai organai taikiniai yra kepenys, inkstai, skydliauk, bluznis ir cirkuliuojantys raudonieji kraujo kneliai.

Repeat-dose toxicity studies in rodents and dogs identified major target organs as the liver, kidney, thyroid, spleen and circulating red blood cells.

Last Update: 2008-03-04
Subject: Medical
Usage Frequency: 3
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Organas Antinksciai Smegenys Krtys Tulzies psls sienel Apatins storosios zarnos sienel Plonoji zarna Skrandis Virsutins storosios zarnos sienel Sirdies sienel Inkstai Kepenys Plauciai Raumuo Kiausids Kasa Kaul smegenys Kaul pavirsiai Oda Bluznis Sklids Uzkrcio liauka Skydliauk Slapimo psls sienel Gimda Visas knas Veiksminga doz

Adrenals Brain Breasts Gallbladder wall Lower large intestine wall Small intestine Stomach Upper large intestine wall Heart wall Kidneys Liver Lungs Muscle Ovaries Pancreas Bone marrow Bone surfaces Skin Spleen Testes Thymus Thyroid Urinary bladder wall Uterus Total body Effective Dose

Last Update: 2008-03-04
Subject: Medical
Usage Frequency: 1
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· hepatomegalija (padidjusios kepenys) ar splenomegalija (padidjusi bluznis) .

· hepatomegaly (enlarged liver) or splenomegaly (enlarged spleen) .

Last Update: 2008-03-04
Subject: Medical
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Cerezyme vartojamas gydyti ligonius, sergancius patvirtinta I ir III tipo Gose liga ir kuriems pasireiskia viens ar keli ligos pozymiai: mazakraujyst (kraujyje mazai raudonj kraujo lsteli) , padidjs polinkis kraujavimui (dl sumazjusio trombocit ­ tam tikr kraujo lsteli ­ skaiciaus) , padidjusios kepenys arba bluznis, kaul pazeidimas.

Cerezyme is used to treat patients who have a confirmed diagnosis of Type I or Type 3 Gaucher disease, and who show signs of the disease such as: anaemia (low number of red blood cells) , a tendency to bleed easily (due to low numbers of platelets -a type of blood cell) , spleen or liver enlargement or bone disease.

Last Update: 2008-03-04
Subject: Medical
Usage Frequency: 1
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Cerezyme vartojamas gydyti ligonius, sergancius patvirtinta I ir III tipo Gose liga ir kuriems pasireiskia viens ar keli ligos pozymiai: mazakraujyst (kraujyje mazai raudonj kraujo lsteli) , padidjs polinkis kraujavimui (dl sumazjusio trombocit ­ tam tikr kraujo lsteli ­ skaiciaus) , padidjusios kepenys arba bluznis, kaul pazeidimas.

Cerezyme is used to treat patients who have a confirmed diagnosis of Type I or Type 3 Gaucher disease, and who show signs of the disease such as: anaemia (low number of red blood cells) , a tendency to bleeding easily (due to low numbers of platelets­ a type of blood cell) , spleen or liver enlargement or bone disease.

Last Update: 2008-03-04
Subject: Medical
Usage Frequency: 1
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Daznas salutinis poveikis (pasireisks nuo 1 iki 10 pacient is 100): periferiniai neurologiniai simptomai (rank ir koj tirpimas, silpnumas, dilgciojimas ar skausmas) , galvos skausmas, nemiga (negaljimas uzmigti); skler gelta (akies baltym pageltimas); vmimas, viduriavimas, pilvo skausmas (skrandzio skausmas ar diskomfortas) , pykinimas, dispepsija (virskinimo sutrikimas); gelta (odos ir/ar aki pageltimas); brimas; lipodistrofijos sindromas (kno pokyciai dl riebalinio audinio persiskirstymo, kaupimosi ar netekimo) , astenija (neprastas nuovargis ar silpnumas) , stiprus nuovargis.Nedaznas salutinis poveikis (pasireisks nuo 1 iki 10 pacient is 1000): alergin reakcija; kno svorio sumazjimas ar padidjimas, anoreksija (apetito netekimas) , apetito padidjimas; depresija, nerimas, miego sutrikimas; sumisimas, amnezija (atminties praradimas) , galvos svaigimas, somnolencija (mieguistumas) , nenormals sapnai; sinkop (nualpimas) , hipertenzija (padidjs kraujospdis); dusulys (oro trkumas); pankreatitas (kasos uzdegimas) , gastritas (skrandzio gleivins uzdegimas) , opinis stomatitas (burnos gleivins isopjimas ir zaizdos) , dizgeuzija (skonio jutimo sutrikimas) , meteorizmas (pilvo ptimas); hepatitas (kepen uzdegimas); dilglin (nieztintis brimas) , alopecija (neprastas plauk slinkimas ar silpnjimas) , niezulys (niezjimas); raumen atrofija (raumen sumazjimas) , artralgija (snari skausmas) , mialgija (raumen skausmas); nefrolitiaz (akmen susidarymas inkstuose) , hematurija (kraujo atsiradimas slapime) , proteinurija (padidjs baltymo kiekis slapime) , poliakiurija (padaznjs slapinimasis); ginekomastija (padidjusios krtys vyrams); krtins skausmas, negalavimas (prasta bendra savijauta) , karsciavimas.Retas salutinis poveikis (pasireisks nuo 1 iki 10 pacient is 10 000): pusiausvyros sutrikimas (nenormali eisena); edema (patinimas) , juntamas sirdies plakimas (padaznjusi ir nereguliari sirdies veikla); pilvo ptimas; hepatosplenomegalija (padidjusios kepenys ir bluznis); pslinis brimas (matomas skyscio susikaupimas po oda) , egzema (odos brimas) , vazodilatacija (kraujagysli issipltimas); miopatija (raumen skausmas ir jgos sumazjimas, nesukelti fizini pratim) , inkst skausmas.

Common (affects 1 to 10 users in 100): peripheral neurologic symptoms (numbness, weakness, tingling or pain in the arms and legs) , headache, insomnia (difficulty sleeping) scleral icterus (presence of jaundice seen in the white part of the eyes) vomiting, diarrhoea, abdominal pain (stomach pain of discomfort) , nausea, dyspepsia (indigestion) jaundice (yellowing of the skin and/or eyes) rash lipodistrophy syndrome (body changes due to fat redistribution, accumulation, or loss of body fat) , asthenia (unusual tiredness or weakness) , fatigue (extreme tiredness) Uncommon (affects 1 to 10 users in 1,000): allergic reaction weight decreased, weight gain, anorexia (loss of appetite) , appetite increased depression, anxiety, sleep disorder confusion, amnesia (loss of memory) , dizziness, somnolence (sleepiness) , abnormal dream syncope (fainting) , hypertension (high blood pressure) dyspnea (shortness of breath) pancreatitis (inflammation of the pancreas) , gastritis (inflammation of the stomach) , stomatitis aphtous (mouth ulcers and cold sores) , dysgeusia (impairment of the sense of taste) , flatulence (wind) hepatitis (inflammation of the liver) urticaria (itchy rash) , alopecia (unusual hair loss or thinning) , pruritus (itching) muscle atrophy (muscle shrinkage) , arthralgia (joint pain) , myalgia (aching muscles) nephrolithiasis (formation of kidney stones) , hematuria (blood in the urine) , proteinuria (excess protein in the urine) , pollakiuria (increased frequency of urination) gynectomastia (breast enlargement in men) chest pain, malaise (generally feeling unwell) , fever Rare (affects 1 to 10 users in 10,000): abnormal gait (abnormal manner of walking) oedema (swelling) , palpitation (fast or irregular heart beat) abdominal distention hepatosplenomegaly (enlargement of the liver and spleen) vesiculobullous rash (visible accumulation of fluid under the skin) , eczema (skin rash) , vasodilatation (widening of blood vessels) myopathy (aching muscles, muscle tenderness of weakness, not caused by exercise) kidney pain

Last Update: 2008-03-04
Subject: Medical
Usage Frequency: 4
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Organas Antinksciai Bluznis Gimda Inkstai Kasa Kaul pavirsius Kepenys Kiausids Krtin Kylancios storosios zarnos sienel Miokardo sienel Nusileidziancios storosios zarnos sienel Oda Plauciai Plonasis zarnynas Raudonieji kaul ciulpai Raumenys Sklids Skrandis Skydliauk Slapimo psls sienel Smegenys Tulzies psl Uzkrtis Efektyvi doz (mSv/MBq) Sio preparato efektyvi doz, suleidus 2

Organ Adrenals Brain Chest Gallbladder Ascending colon wall Descending colon wall Small intestine Myocardial wall Kidneys Liver Lungs Muscle Ovaries Pancreas Red marrow Bone surfaces Skin Spleen Stomach Testes Thymus Thyroid Urinary bladder wall Uterus Effective dose (mSv/MBq)

Last Update: 2008-03-04
Subject: Medical
Usage Frequency: 1
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Organas Antinksciai Kraujas Kaul ciulpai Smegenys Griauciai Gaubtin zarna Slaunikaulis Virskinamojo trakto turinys Sirdis Klubin zarna Inkstai Kepenys Plauciai Kiausids Kasa Griauci raumuo Oda Bluznis Skrandis Uzkrcio liauka Skydliauk Slapimo psl Gimda Efektyvi doz (mSv/MBq)

OrganAdult15 years10 years 5 years 1 year5 years 10 years 5 years1 yearNewbornAdrenals Blood Bone marrow Brain Carcass Colon Femur Gastro-intestinal content Heart Ileum Kidneys Liver Lungs Ovaries Pancreas Skeletal muscle Skin Spleen Stomach Thymus Thyroids Urinary bladder Uterus Effective Dose (mSv/MBq)

Last Update: 2008-03-04
Subject: Medical
Usage Frequency: 1
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Pakartotinai skiriant leflunomido per os pelms (iki 3 mnesi) , ziurkms ir sunims (iki 6 mnesi) bei bezdzionms (iki mnesio) , nustatyta, kad dl toksinio poveikio labiausiai pazeidziami kaul ciulpai, kraujas, virskinimo traktas, oda, bluznis, uzkrcio liauka ir limfmazgiai.

Repeated oral administration of leflunomide to mice for up to 3 months, to rats and dogs for up to 6 months and to monkeys for up to 1 month 's duration revealed that the major target organs for toxicity were bone marrow, blood, gastrointestinal tract, skin, spleen, thymus and lymph nodes.

Last Update: 2008-03-04
Subject: Medical
Usage Frequency: 3
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Rekomenduojama doz -2 milijonai TV/m2 pood tris kartus per savait (kas antr dien) neatsizvelgiant tai, ar ligoniui pasalinta bluznis, ar ne.

The recommended dosage is 2 million IU/m2 administered subcutaneously three times a week (every other day) for both splenectomised and non-splenectomised patients.

Last Update: 2008-03-04
Subject: Medical
Usage Frequency: 11
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Rekomenduojama doz -2 milijonai TV/m2 pood tris kartus per savait (kas antr dien) neatsizvelgiant tai, ar ligoniui pasalinta bluznis, ar ne.

The recommended dosage is 2 million IU/m2 administered subcutaneously three times a week (every other day) for both splenectomised and non-splenectomised patients.For

Last Update: 2008-03-04
Subject: Medical
Usage Frequency: 3
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