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perjimas kit gydymo grup buvo leidziamas nustacius ligos progresavim arba vaisto netoleravim, kurio nebuvo galima sureguliuoti modifikuojant doz.
crossover to the alternative treatment arm was allowed if patients showed evidence of disease progression or intolerance that could not be managed by dose modification.
Last Update: 2008-03-04
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perjimas nuo gydymo ciklosporinu keiciant pacient gydym ciklosporinu gydym (sugalvotas) pavadinimas , reikia laikytis atsargumo (zr.
conversion from ciclosporin care should be taken when converting patients from ciclosporin-based to invented name -based therapy (see sections 4.4 and 4.5) . invented name therapy should be initiated after considering ciclosporin blood concentrations and the clinical condition of the patient.
Last Update: 2008-03-04
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atliekant klinikin tyrim, kuriuo buvo vertinamas palaikomajam gydymui po inksto persodinimo pradedamas rapamune vartojimas vietoj kalcineurino inhibitori, paprastai prajus nuo 6 iki 24 mnesiams nuo perjimo prie rapamune vartojimo buvo pastebimas padidjs baltym issiskyrimas su slapimu (zr.5. 1 skyri) .
in a study evaluating conversion from calcineurin inhibitors to rapamune in maintenance renal transplant patients, increased urinary protein excretion was commonly observed at 6 to 24 months after conversion to rapamune (see section 5.1) .
Last Update: 2008-03-04
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