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deve evitar- se a administração concomitante de isotretinoína com agentes anti- acneicos tópicos, de acção queratolítica uma vez que a irritação local poderá aumentar.
musculo-skeletal and connective tissue disorders myalgia, arthralgia and increased serum creatine phosphokinase values have been reported in patients receiving isotretinoin, particularly in those undertaking vigorous physical activity (see section 4.8 “ undesirable effects”).
Last Update: 2012-04-12
Usage Frequency: 2
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deve evitar- se a administração concomitante de isotretinoína com agentes anti- acneicos tópicos, de acção queratolítica ou exfoliativa, uma vez que a irritação local pode aumentar.
concurrent administration of isotretinoin with topical keratolytic or exfoliative anti-acne agents should be avoided as local irritation may increase.
Last Update: 2012-04-12
Usage Frequency: 2
Quality:
Warning: This alignment may be wrong.
Please delete it you feel so.