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iatrogénna závislosť po terapeutickom použití opiátov je zriedkavá.
iatrogenic addiction following therapeutic use of opioids is rare.
Last Update: 2012-04-12
Usage Frequency: 2
Quality:
iatrogénny návyk po terapeutickom použití opioidov je však zriedkavý.
however, iatrogenic addiction following therapeutic use of opioids is rare.
Last Update: 2017-04-26
Usage Frequency: 1
Quality:
101 primeranom individuálnom diagnostickom a terapeutickom zvládnutí psychiatrického ochorenia.
the use of interferon alfa-2b in children and adolescents with existence of or history of severe psychiatric conditions is contraindicated (see section 4.3).
Last Update: 2011-10-23
Usage Frequency: 5
Quality:
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brimonidín však prejavuje lineárnu farmakokinetiku v klinicky terapeutickom rozsahu dávky.
in contrast, brimonidine exhibits linear pharmacokinetics over the clinically therapeutic dose range.
Last Update: 2017-04-26
Usage Frequency: 1
Quality:
pozorované toxikologické nálezy pravdepodobne nemajú význam pri terapeutickom použití u ľudí.
the toxicological findings observed appear to have no relevance to human therapeutic use.
Last Update: 2017-04-26
Usage Frequency: 3
Quality:
v terapeutickom rozsahu sú plazmatické koncentrácie približne úmerné rozsahu terapeutickej dávky.
plasma concentrations are approximately dose proportional over the therapeutic dose range.
Last Update: 2017-04-26
Usage Frequency: 3
Quality:
13 linearita zvýšenie priemernej auc je v terapeutickom rozmedzí lineárne a úmerné dávke.
linearity the increase in mean auc is linear and dose proportional in the therapeutic range.
Last Update: 2012-04-12
Usage Frequency: 8
Quality:
v ľudskej plazme predstavuje voľná frakcia asi 2,0 % pri terapeutickom rozmedzí koncentrácií.
in human plasma the unbound fraction is about 2.0% in the therapeutic concentration range.
Last Update: 2017-04-26
Usage Frequency: 3
Quality:
expozícia (auc) aktívneho metabolitu sa zvyšuje úmerne s dávkou v terapeutickom rozmedzí.
the active metabolite’s exposure (auc) increases proportionally over the therapeutic dose range.
Last Update: 2017-04-26
Usage Frequency: 3
Quality:
kombinácia hydrochlorotiazidu a irbesartanu v ich terapeutickom rozsahu dávok spôsobuje od dávky závislé aditívne zníženie krvného tlaku.
the combination of hydrochlorothiazide and irbesartan produces dose-related additive reductions in blood pressure across their therapeutic dose ranges.
Last Update: 2017-04-26
Usage Frequency: 17
Quality:
hladina ustáleného stavu v terapeutickom rozmedzí sa dosiahne pri podávaní toujeo raz denne po 3-4 dňoch.
steady state level within the therapeutic range is reached after 3-4 days of daily toujeo administration.
Last Update: 2017-04-26
Usage Frequency: 1
Quality:
v terapeutickom rozsahu dávkovania lamivudínu je jeho farmakokinetika lineárna a väzba na plazmatický albumín obmedzená (< 36% sérového albumínu
lamivudine exhibits linear pharmacokinetics over the therapeutic dose range and displays limited binding to the major plasma protein albumin (< 36% serum albumin in vitro).
Last Update: 2012-04-12
Usage Frequency: 2
Quality:
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v terapeutickom rozsahu dávkovania lamivudínu je jeho farmakokinetika lineárna a väzba na plazmatické bielkoviny in vitro je obmedzená (< 36 %).
lamivudine exhibits linear pharmacokinetics over the therapeutic dose range and displays limited plasma protein binding in vitro (< 36%).
Last Update: 2017-04-26
Usage Frequency: 3
Quality:
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v ramene liečby pri terapeutickom dávkovaní 11 % probandov a pri supraterapeutickom dávkovaní 18 % probandov malo qtcs v rozmedzí od 450 po 480 ms.
in the therapeutic and the supra-therapeutic arm 11% and 18% of subjects, respectively, had a qtcs between 450 and 480 msec.
Last Update: 2017-04-26
Usage Frequency: 1
Quality:
u pacientov randomizovaných na warfarín bol medián času v terapeutickom rozsahu (inr 2,0 až 3,0) 60,6 %.
for patients randomized to warfarin, the median time in therapeutic range (inr 2.0 to 3.0) was 60.6 %.
Last Update: 2017-04-26
Usage Frequency: 2
Quality:
u pacientov randomizovaných na warfarín bol medián času v terapeutickom rozsahu (inr 2,0-3,0) 64,9 %.
for patients randomized to warfarin, the median time in therapeutic range (inr 2.0-3.0) was 64.9 %.
Last Update: 2017-04-26
Usage Frequency: 1
Quality:
farmakokinetika tolkaponu je v terapeutickom rozsahu lineárna a nezávisí od súčasného podávania levodopy/ aadc- 1 (benserazid alebo karbidopa).
in the therapeutic range, tolcapone pharmacokinetics are linear and independent of levodopa/ aadc-i (benserazide or carbidopa) coadministration.
Last Update: 2011-10-23
Usage Frequency: 1
Quality:
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v skupine liečenej warfarínom, medián ttr (čas v terapeutickom rozmedzí, inr 2,0-3,0) bol 65,6%.
in the warfarin group, the median ttr (time in therapeutic range, inr 2.0 to 3.0) was 65.6%.
Last Update: 2017-04-26
Usage Frequency: 2
Quality:
medián percenta času, kedy boli pacienti randomizovaní na warfarín v terapeutickom rozsahu (ttr) (inr 2 - 3), bol 66 %.
for patients randomised to warfarin, the median percentage of time in therapeutic range (ttr) (inr 2-3) was 66%.
Last Update: 2017-04-26
Usage Frequency: 1
Quality: