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Al impedir el funcionamiento de esta enzima, el miglustat reduce la producción de glucoesfingolípidos en las células.

By preventing the enzyme from working, miglustat can reduce the production of glycosphingolipids in cells.

Last Update: 2012-04-10
Subject: Pharmaceuticals
Usage Frequency: 1
Quality:
Reference: EMEA

Las manifestaciones neurológicas se consideran secundarias a la acumulación anormal de glucoesfingolípidos las neuronas y células de la glía.

The neurological manifestations are considered secondary to the abnormal accumulation of glycosphingolipids in neuronal and glial cells.

Last Update: 2012-04-10
Subject: Pharmaceuticals
Usage Frequency: 1
Quality:
Reference: EMEA

Zavesca actúa inhibiendo la enzima denominada glucosilceramida sintetasa, responsable del primer paso en la síntesis de la mayoría de glucoesfingolípidos.

Zavesca works by inhibiting the enzyme called ‘ glucosylceramide synthase’ which is responsible for the first step in the synthesis of most glycosphingolipids.

Last Update: 2012-04-10
Subject: Pharmaceuticals
Usage Frequency: 1
Quality:
Reference: EMEA

Si los componentes elegidos del fermento han sido aislados y purificados de forma significativa y existen pruebas analíticas, puede utilizarse el nombre de uno o más de los componentes, por ejemplo Glycosphingolipids (glucoesfingolípidos), Beta-Glucan (betaglucano) o Dextran (dextrano).

If the selected components of the ferment have been isolated and purified to a significant extent and analytical evidence is provided, the name for one or more of the components may be used, e.g. Glycosphingolipids, Beta-Glucan or Dextran.

Last Update: 2014-11-07
Subject: Social Science
Usage Frequency: 1
Quality:
Reference: DGT-TM

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