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Las personas inmunocomprometidas/ inmunosuprimidas no pueden ser autorizadas a manipular esta vacuna.

Immunocompromised/ immunosuppressed individuals must not be allowed to handle this vaccine.

Last Update: 2012-04-10
Subject: Pharmaceuticals
Usage Frequency: 1
Quality:
Reference: EMEA

Se indicará toda experiencia sobre el efecto tóxico de la sustancia activa o sus productos metabólicos en el hombre o en animales, sobre si el organismo es capaz de colonizar o invadir al hombre o a los animales (incluidos los individuos inmunosuprimidos) y sobre si es patógeno.

Any experience of the toxic effect of the active substance or its metabolic products on humans or animals, of whether the organism is capable of colonising or invading humans or animals (including immunosuppressed individuals) and whether it is pathogenic shall be stated.

Last Update: 2014-10-18
Subject: Social Science
Usage Frequency: 3
Quality:
Reference: DGT-TM

Los pacientes inmunosuprimidos tienen deficiencias en las defensas del huésped como resultado de una inmunodeficiencia subyacente o la administración de fármacos (sobre todo relacionadas con el trasplante de órganos y la quimioterapia para el cáncer).51,91 Puesto que la quimioterapia suele ser citotóxica para la médula espinal, la destrucción de las plaquetas y los glóbulos blancos y rojos produce trombocitopenia, anemia y leucopenia.

Immunosuppressed patients have impaired host defenses as a result of an underlying immunodeficiency or drug administration (primarily related to organ transplantation or cancer chemotherapy).57,91 Because chemotherapy is often cytotoxic to bone marrow, destruction of platelets and red and white blood cells results in thrombocytopenia, anemia, and leukopenia.

Last Update: 2014-04-05
Subject: Medical
Usage Frequency: 1
Quality:
Reference: Andrm
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Los individuos inmunosuprimidos están en mayor riesgo de infección, e incluso las infecciones periodontales menores pueden amenazar la vida si la inmunosupresión es grave.75,78 Se pueden manifestar infecciones intrabúcales, bacterianas, virales y micosis.

Immunosuppressed individuals are at greatly increased risk for infection, and even minor periodontal infections can become life threatening if immunosuppression is severe.75,78 Intraorally, bacterial, viral, and fungal infections may manifest.

Last Update: 2014-04-05
Subject: Medical
Usage Frequency: 1
Quality:
Reference: Andrm
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Debido a que casi ninguna infección de hepatitis se diagnostica, el periodoncista debe ser consciente de los grupos de alto riesgo, como los pacientes en diálisis renal, los trabajadores del cuidado de la salud, los pacientes inmunosuprímidos, los pacientes que han recibido múltiples transfusiones sanguíneas, homosexuales, usuarios de drogas y pacientes internados.

Because the majority of hepatitis infections are undiagnosed, the clinician must be aware of high-risk groups, such as renal dialysis patients, health care workers, immunosuppressed patients, patients who have received multiple blood transfusions, homosexuals, drug users, and institutionalized patients.

Last Update: 2014-04-05
Subject: Medical
Usage Frequency: 1
Quality:
Reference: Andrm
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Infecciones Los pacientes podrían estar inmunosuprimidos, por lo que deberán ser observados cuidadosamente en cuanto a la presentación de infecciones, incluidas infecciones oportunistas.

4 Infections Patients may be immunosuppressed and should be carefully observed for the occurrence of infections, including opportunistic infections.

Last Update: 2012-04-10
Subject: Pharmaceuticals
Usage Frequency: 1
Quality:
Reference: EMEA

El CHMP consideró que la indicación terapéutica « descontaminación digestiva selectiva en pacientes inmunosuprimidos » no podía aceptarse, puesto que el solicitante/ MAH no ha aportado datos específicos que respalden dicho uso terapéutico, y no existe consenso en la comunidad científica sobre el uso de ciprofloxacino en este contexto.

The CHMP was of the opinion that the therapeutic indication “ selective digestive decontamination in immuno-suppressed patients” could not be accepted, as there is an absence of specific data submitted by the Applicant/ MAH to support such therapeutic use and there is no consensus in the scientific community on the use ciprofloxacin in such indication.

Last Update: 2012-04-10
Subject: Pharmaceuticals
Usage Frequency: 1
Quality:
Reference: EMEA

El riesgo aumenta en pacientes que ya están inmunosuprimidos por su enfermedad subyacente.Fenitoína: el uso concomitante de medicamentos citotóxicos podría reducir la absorción de la fenitoína y agravar las convulsiones.

This risk is increased in subjects who are already immunosuppressed by their underlying disease Phenytoin: concomitant use of cytotoxic medicinal products may reduce the absorption of phenytoin leading to an exacerbation of convulsions.

Last Update: 2008-03-04
Subject: Medical
Usage Frequency: 1
Quality:
Reference: EMEA
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trasplante y que se encuentran inmunosuprimidos.-Enfermedad tiroidea preexistente, salvo que pueda controlarse con tratamiento convencional

-Pre-existing thyroid disease unless it can be controlled with conventional treatment.

Last Update: 2008-03-04
Subject: Medical
Usage Frequency: 12
Quality:
Reference: EMEA
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