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tibolona

tibolone

Last Update: 2014-11-04
Subject: Medical
Usage Frequency: 4
Quality:
Reference: IATE

El tratamiento concomitante para la osteoporosis incluyó: calcitonina, raloxifeno, tamoxifeno, terapia hormonal sustitutiva, tibolona; pero se excluyeron otros bisfosfonatos.

Concomitant osteoporosis therapy included: calcitonin, raloxifene, tamoxifen, hormone replacement therapy, tibolone; but excluded other bisphosphonates.

Last Update: 2012-04-10
Subject: Pharmaceuticals
Usage Frequency: 1
Quality:
Reference: EMEA

El estudio MWS informó que, comparado con no usuarias, el uso de distintos tipos de la THS combinada estrógenos– progestágenos estuvo asociada con un riesgo superior de cáncer de mama ((RR= 2.00, 95% CI (1.88-2.12)) que con el uso de estrógenos solos ((RR= 1.30, 95% CI (1.21 -1.40)) o con el uso de tibolona ((RR= 1.45; 95% CI (1.25-1.68)).

The MWS reported that, compared to never users, the use of various types of oestrogen-progestagen combined HRT was associated with a higher risk of breast cancer (RR = 2.00, 95%CI 1.88 – 2.12) than use of oestrogens alone (RR = 1.30, 95%CI 1.21 – 1.40) or use of tibolone (RR=1.45, 95%CI 1.25 – 1.68).

Last Update: 2012-04-10
Subject: Pharmaceuticals
Usage Frequency: 1
Quality:
Reference: EMEA

Se ha informado de un aumento de riesgo de cáncer de mama en mujeres que toman estrógenos, combinaciones de estrógenos-progestágenos o tibolona como THS durante varios años, a través de un ensayo randomizado, placebo-controlado, llamado Women´s Health Initiative Study (WHI), y estudios epidemiológicos, incluyendo el Million Woman Study (MWS) (ver Sección 4.8).

Breast cancer A randomised placebo-controlled trial, the Women’s Health Initiative study (WHI), and epidemiological studies, including the Million Women Study (MWS), have reported an increased risk of breast cancer in women taking oestrogens, oestrogen-progestagen combinations or tibolone for HRT for several years (see section 4.8).

Last Update: 2012-04-10
Subject: Pharmaceuticals
Usage Frequency: 1
Quality:
Reference: EMEA

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