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tibolona

tibolone

Last Update: 2014-11-04
Subject: Medical
Usage Frequency: 4
Quality:
Reference: IATE

El tratamiento concomitante para la osteoporosis incluyó: calcitonina, raloxifeno, tamoxifeno, terapia hormonal sustitutiva, tibolona; pero se excluyeron otros bisfosfonatos.
http://www.emea.europa.eu/

Concomitant osteoporosis therapy included: calcitonin, raloxifene, tamoxifen, hormone replacement therapy, tibolone; but excluded other bisphosphonates.
http://www.emea.europa.eu/

Last Update: 2012-04-10
Subject: Pharmaceuticals
Usage Frequency: 1
Quality:
Reference: europa.eu

El estudio MWS informó que, comparado con no usuarias, el uso de distintos tipos de la THS combinada estrógenos– progestágenos estuvo asociada con un riesgo superior de cáncer de mama ((RR= 2.00, 95% CI (1.88-2.12)) que con el uso de estrógenos solos ((RR= 1.30, 95% CI (1.21 -1.40)) o con el uso de tibolona ((RR= 1.45; 95% CI (1.25-1.68)).
http://www.emea.europa.eu/

The MWS reported that, compared to never users, the use of various types of oestrogen-progestagen combined HRT was associated with a higher risk of breast cancer (RR = 2.00, 95%CI 1.88 – 2.12) than use of oestrogens alone (RR = 1.30, 95%CI 1.21 – 1.40) or use of tibolone (RR=1.45, 95%CI 1.25 – 1.68).
http://www.emea.europa.eu/

Last Update: 2012-04-10
Subject: Pharmaceuticals
Usage Frequency: 1
Quality:
Reference: europa.eu

Se ha informado de un aumento de riesgo de cáncer de mama en mujeres que toman estrógenos, combinaciones de estrógenos-progestágenos o tibolona como THS durante varios años, a través de un ensayo randomizado, placebo-controlado, llamado Women´s Health Initiative Study (WHI), y estudios epidemiológicos, incluyendo el Million Woman Study (MWS) (ver Sección 4.8).
http://www.emea.europa.eu/

Breast cancer A randomised placebo-controlled trial, the Women’s Health Initiative study (WHI), and epidemiological studies, including the Million Women Study (MWS), have reported an increased risk of breast cancer in women taking oestrogens, oestrogen-progestagen combinations or tibolone for HRT for several years (see section 4.8).
http://www.emea.europa.eu/

Last Update: 2012-04-10
Subject: Pharmaceuticals
Usage Frequency: 1
Quality:
Reference: europa.eu

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