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al anticuerpo se pueden acoplar agentes terapéuticos tales como radioisótopos mediante medios directos o mediante medios indirectos (por ejemplo, a través de un agente quelante) mediante cualquier técnica apropiada, tal como el procedimiento con <PROTECTED> o con benzoato de nsuccinimidil3(trinbutilestanilo) (“procedimiento <PROTECTED>”), tal como será obvio para los expertos en la técnica.
therapeutic agents such as radioisotopes may be coupled to the antibody by direct means or indirect means (e.g., via a chelator) by any suitable technique, such as the <PROTECTED> method or with n succinimidyl-3- (tri-n-butylstanyl) benzoate (the "<PROTECTED> method"), as will be apparent to those skilled in the art.