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telmisartan er stærkt lipofil og har en hurtig membranpermeabilitetskinetik, hvilket letter distributionen ind i væv.
telmisartan is highly lipophilic and has rapid membrane permeability kinetics, which facilitates easy distribution into tissue.
fentanyl er stærkt lipofil og fordeles godt ud over det vaskulære system med et stort tilsyneladende fordelingsvolumen.
fentanyl is highly lipophilic and is well distributed beyond the vascular system, with a large apparent volume of distribution.
darifenacin er en lipofil base, 98% er bundet til plasmaproteiner (primært alfa-1-syre-glycoprotein).
darifenacin is a lipophilic base and is 98% bound to plasma proteins (primarily to alpha-1-acid- glycoprotein).
fordeling darifenacin er en lipofil base, 98% er bundet til plasmaproteiner (primært alfa- 1- syre- glycoprotein).
distribution darifenacin is a lipophilic base and is 98% bound to plasma proteins (primarily to alpha-1-acid- glycoprotein).
patienten bør følges nøje, idet man tager højde for, at svækkelsen er reversibel, men den lange halveringstid og mitotans lipofile natur taget i betragtning, kan det tage uger at vende tilbage normal tilstand.
the patient should be followed closely, taking into account that impairment is reversible, but given the long half-life and the lipophilic nature of mitotane, it may take weeks to return to normal.