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Results for vacuolation translation from English to Maltese

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English

Phospholipidosis (vacuolation of the cells of the liver, adrenal gland and lung) also occurred.

Maltese

Fosfolipidosi (vakuwolazzjoni taċ-ċelluli tal-fwied, glandoli adrenali u l- pulmun) seħħet ukoll.

Last Update: 2017-04-26
Usage Frequency: 1
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English

Increased cellular vacuolation of the adrenal gland zona glomerulosa was observed during the 13-week toxicity study in rats.

Maltese

Żieda fil-vakwolazzjoni ċellulari taż-żona glomerulosa tal-glandola adrenali kienet osservata waqt l-istudju ta’ tossiċità ta’ 13-il ġimgħa fil- firien.

Last Update: 2017-04-26
Usage Frequency: 3
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English

No functional impairment was observed and electron microscopic investigations of the rat kidneys indicated that the observed vacuolation was primarily a storage phenomenon.

Maltese

L-ebda indeboliment funzjonali ma kien osservat, u investigazzjoni tal-kliewi tal-firien permezz ta’ mikroskopju tal-elettroni, indikat li l-vakwolazzjoni osservata kienet primarjament fenomenu tal-ħażna.

Last Update: 2017-04-26
Usage Frequency: 1
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English

No functional impairment was observed and electron microscopic investigations of the rat kidneys indicated that the observed vacuolation was primarily a storage phenomenon.

Maltese

L- ebda indeboliment funzjonali ma kien osservat, u investigazzjoni tal- kliewi tal- firien permezz ta ’ mikroskopju ta ’ l- elettroni, indikat li l - vakwolazzjoni osservata kienet primarjament fenomenu tal- ħażna.

Last Update: 2012-04-10
Usage Frequency: 2
Quality:

English

However reversible hypospermia and testicular vacuolation and immaturity of the ovaries were observed in a repeat-dose toxicity study with fenofibric acid in young dogs.

Maltese

Madankollu kienu osservati ipospermja u vakulazzjoni testikulari riversibbli u immaturità tal-ovarji fi studji ta’ tossiċità b’dożi ripetuti b’fenofibric acid fil-klieb żgħar.

Last Update: 2017-04-26
Usage Frequency: 1
Quality:

English

Repeated-dose toxicity studies revealed vacuolation of the tubular cells of the kidneys, with strong evidence for reversibility of the effect.

Maltese

Studji dwar it-tossiċità meta jingħataw dożi ripetuti żvelaw il-vakwolazzjoni taċ-ċelluli tubulari

Last Update: 2017-04-26
Usage Frequency: 1
Quality:

English

Degeneration in the stomach and hepatocyte vacuolation were observed in rats following 6 months of dosing at systemic exposure values at least 179 times the human exposure based on the AUC of the recommended daily human dose.

Maltese

Kienet osservata deġenerazzjoni fl-istonku u vakwolazzjoni ta’ l-epatoċiti fil-firien wara 6 xhur ta’ dożaġġ b’valuri ta’ esponiment sistemiku ta’ mill-anqas 179 darba l-esponiment uman ibbażat fuq l- AUC tad-doża ta’ kuljum rakkomandata għall-bnedmin.

Last Update: 2017-04-26
Usage Frequency: 1
Quality:

English

Repeated-dose toxicity studies in rats and dogs revealed vacuolation of the tubular cells of the kidneys, with strong evidence for reversibility of the effect.

Maltese

Studji dwar it-tossiċità meta ngħataw dożi ripetuti fil-firien u fil-klieb, żvelaw il-vakwolazzjoni taċ- ċelluli tubulari tal-kliewi, b’evidenza qawwija għar-riversibbiltà ta’ l-effett.

Last Update: 2017-04-26
Usage Frequency: 3
Quality:

English

Repeated dose toxicity Repeated-dose toxicity studies revealed vacuolation of the tubular cells of the kidneys, with strong evidence for reversibility of the effect.

Maltese

Tossiċità ta ’ doża ripetuti Studji dwar it- tossiċità meta jingħataw dożi ripetuti żvelaw il- vakwolazzjoni taċ- ċelluli tubulari tal - kliewi, b’ evidenza qawwija għar- riversibbiltà ta ’ l- effett.

Last Update: 2012-04-10
Usage Frequency: 2
Quality:

English

Nicotinic acid Degeneration in the stomach and hepatocyte vacuolation were observed in rats following 6 months of dosing at systemic exposure values at least 179 times the human exposure based on the AUC of the recommended daily human dose.

Maltese

Aċidu nikotiniku Kienet osservata deġenerazzjoni fl- istonku u vakwolazzjoni ta ’ l- epatoċiti fil- firien wara 6 xhur ta ’ dożaġġ b’ valuri ta ’ esponiment sistemiku ta ’ mill- anqas 179 darba l- esponiment uman ibbażat fuq l - AUC tad- doża ta ’ kuljum rakkomandata għall- bnedmin.

Last Update: 2012-04-10
Usage Frequency: 2
Quality:

English

Repeated-dose toxicity studies in rats and dogs revealed vacuolation of the tubular cells of the kidneys, with strong evidence for reversibility of the effect.

Maltese

18 Studji dwar it- tossiċità meta jingħataw dożi ripetuti fil- firien u fil- klieb, żvelaw il- vakwolazzjoni taċ - ċelluli tubulari tal- kliewi, b’ evidenza qawwija għar- riversibbiltà ta ’ l- effett.

Last Update: 2012-04-10
Usage Frequency: 2
Quality:

English

Preclinical data on the intravenous vehicle SBECD indicated that the main effects were vacuolation of urinary tract epithelium and activation of macrophages in the liver and lungs in the repeated-dose toxicity studies.

Maltese

Tagħrif prekliniku fuq il-prodott li jiddaħħal ġol-vini, SBECD indika li l-effetti prinċipali keinu vakulazzjoni fl-epitelju tal-passaġġ ta' l-awrina u attivazzjoni ta' makrofagi fil-fwied u pulmuni fl- istudji tat-tossiċità ta' doża ripetuta.

Last Update: 2017-04-26
Usage Frequency: 3
Quality:

English

Phospholipidosis (vacuolation of lymphoid tissue) also occurred; although this was not related to clinical signs in dogs treated up to 6 months.

Maltese

Il-fosfolipidożi seħħet ukoll (vakwolazzjoni tat-tessut limfojde); għalkemm din ma kinitx relatata ma’ sinjali kliniċi fil-klieb ikkurati għal sa 6 xhur.

Last Update: 2017-04-26
Usage Frequency: 1
Quality:

English

Phospholipidosis (vacuolation of lymphoid tissues) also occurred; although this was not related to clinical signs in dogs treated up to 6 months.

Maltese

Il-fosfolipidożi seħħet ukoll (vakwolazzjoni tat-tessut limfojdi); għalkemm din ma kinitx relatata ma’ sinjali kliniċi fil-klieb ikkurati għal sa 6 xhur.

Last Update: 2017-04-26
Usage Frequency: 1
Quality:

English

60 Preclinical data on the intravenous vehicle, SBECD indicated that the main effects were vacuolation of urinary tract epithelium and activation of macrophages in the liver and lungs in the repeated-dose toxicity studies.

Maltese

Tagħrif prekliniku fuq il- prodott li jiddaħħal ġol- vini, SBECD indika li l- effetti prinċipali keinu vakulazzjoni fl- epitelju tal- passaġġ ta 'l- awrina u attivazzjoni ta' makrofagi fil- fwied u pulmuni fl - istudji tat- tossiċità ta 'doża ripetuta.

Last Update: 2011-10-23
Usage Frequency: 1
Quality:

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English

Changes were observed in liver (hepatocyte hypertrophy, vacuolation, increased liver enzymes) and thyroid (follicular hypertrophy).

Maltese

Bidliet ġew osservati fil-fwied (ipertrofija ta’ l-epatoċiti, vakwolazzjoni, żieda fl-enzimi tal- fwied) u t-tirojde (ipertrofija follikulari).

Last Update: 2017-04-26
Usage Frequency: 2
Quality:

English

In adult dogs, atrophy of seminiferous tubules with vacuolation of the seminiferous epithelium and decreased sperm in the epididymides were noted after prolonged treatment (39 weeks) but not after 13 weeks of treatment.

Maltese

Fil-klieb adulti, atrofija tat-tubi seminiferi b’vakulazzjoni ta’ l- epitilu seminiferu u anqas sperma fl-epididimidi ġew innotati wara trattament fit-tul (39 ġimgħa), imma mhux wara 13-il ġimgħa ta’ trattament.

Last Update: 2017-04-26
Usage Frequency: 3
Quality:

English

In rats, vacuolation of the renal pelvic epithelium as well as vacuolation and thickening (hyperplasia) of the bladder epithelium were observed in 26-week repeat dose studies.

Maltese

Fil-firien, vakulazzjoni ta’ l-epitelju pelviku renali kif ukoll vakulazzjoni u tħaxxin (iperplasja) ta’ l- epitelju tal-bużżieqa ta’ l-awrina kienu osservati fi studji ta’ 26 ġimgħa b’dożi ripetuti.

Last Update: 2017-04-26
Usage Frequency: 1
Quality:

English

The liver was also affected in both species, at exposures that approximate clinical exposures at the recommended dose of 750 mg, and included minimal increases in liver transaminases in a few animals and vacuolation of the intra-hepatic bile duct epithelium.

Maltese

Il-fwied kien ukoll affettwat fiż-żewġ speċi, f’espożizzjonijiet li japprossimizzaw l-espożizzjonijiet kliniċi fid-doża rrakkomandata ta’ 750 mg, u kienu jinkludu żidiet minimi fit-transaminasi tal-fwied f’xi annimali u vakwolazzjoni tal-passaġġ biljari epitelju intraepatiku.

Last Update: 2017-04-26
Usage Frequency: 1
Quality:

English

In rats, vacuolation of the renal pelvic epithelium as well as vacuolation and thickening (hyperplasia) of the bladder epithelium were observed in 26-week repeat dose studies.

Maltese

Fit- tieni studju

Last Update: 2011-10-23
Usage Frequency: 1
Quality:

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