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after a hormone binds to the corresponding receptor, the newly formed receptor-ligand complex translocates into the cell nucleus, where it binds to many hormone response elements (hres) in the promoter region of the target genes in the dna.
após a ligação da hormonal ao receptor, o complexo ligando-receptor é translocado até ao núcleo celular, onde se liga a elementos de resposta hormonal na região promotora do gene-alvo no dna, estimulando a transcrição.
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