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de bäst validerade tillbakamutationssystemen bygger på användning av den haploida stammen xv 185-14c, som är bärare av de ockra nonsensmutationerna ade 2-1, arg 4-17, lys 1-1 och trp 5-48, som tillbakamuterar med basparsubstitutionsmutagener, som inducerar punktmutationer eller ockra suppressormutationer.
the most extensively validated reverse mutation system involves the use of the haploid strain xv 185-14c which carries the ochre nonsense mutations ade 2-1, arg 4-17, lys 1-1 and trp 5-48, which are reversible by base substitution mutagens that induce site specific mutations or ochre suppressor mutations.
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