Usted buscó: metilprednizolona (Esloveno - Inglés)

verjetno je ta učinek pri peroralnem odmerjanju metilprednizolona izrazitejši.
this effect may be expected to be more pronounced for orally administered methylprednisolone.

sprememb plazemskih koncentracij metilprednizolona v klinično pomembnem obsegu ne pričakujemo.
although the concomitant administration of methylprednisolone with the single 40 mg dose of aprepitant has not been studied, a single 40 mg dose of aprepitant produces a weak inhibition of cyp3a4 and it is not expected to alter the plasma concentrations of methylprednisolone to a clinically significant degree.

pričakujemo lahko, da bo ta učinek pri peroralni uporabi metilprednizolona izrazitejši.
this effect may be expected to be more pronounced for orally administered methylprednisolone.

raloksifen ne vpliva na farmakokinetiko metilprednizolona, ki ga bolnici damo v enkratnem odmerku.
raloxifene has no effect on the pharmacokinetics of methylprednisolone given as a single dose.

raloksifen ne vpliva na farmakokinetiko metilprednizolona, ki ga bolnici damo v enem samem odmerku.
raloxifene has no effect on the pharmacokinetics of methylprednisolone given as a single dose.

poleg tega je treba pol ure pred injiciranjem zdravila glybera uporabiti intravenski bolus z 1 mg/kg metilprednizolona.
in addition, half an hour prior to glybera injection an intravenous bolus of 1mg/kg of methylprednisolone should be administered.

veliki odmerki prednizolona ali metilprednizolona, uporabljeni za zdravljenje akutne zavrnitve, lahko koncentracijo takrolimusa v krvi zvišajo ali znižajo.
high dose prednisolone or methylprednisolone administered for the treatment of acute rejection have the potential to increase or decrease tacrolimus blood levels.

po drugi infuziji je mogoče po zdravnikovi presoji znižati odmerek intravenskega kortikosteroida (odmerek metilprednizolona na 60 mg).
following the second infusion, the dose of intravenous corticosteroid may be reduced (methylprednisolone 60 mg) at the discretion of the physician.

bolniki so 30 minut pred injiciranjem alipogentiparvoveka prejeli enkratni intravenski bolus metilprednizolona (1 mg/kg telesne mase).
a single intravenous bolus of methylprednisolone (1 mg/kg bodyweight) was given 30 minutes prior to alipogene tiparvovec administration.

pri kontinuiranem zdravljenju z metilprednizolonom se lahko kasneje, v dveh tednih po začetku zdravljenja s peroralnim aprepitantom, auc metilprednizolona zmanjša zaradi indukcijskega učinka aprepitanta na cyp3a4.
during continuous treatment with methylprednisolone, the auc of methylprednisolone may decrease at later time points within 2 weeks following initiation of dosing with oral aprepitant, due to the inducing effect of aprepitant on cyp3a4.

v primeru hudega izpuščaja je treba uvesti zdravljenje z visokim odmerkom kortikosteroidov v odmerku, ki ustreza 1 do 2 mg/kg/dan metilprednizolona.
severe rash should be managed with high-dose corticosteroid at a dose of 1 to 2 mg/kg/day methylprednisolone equivalents.

v primeru suma na akutno vnetje hipofize je treba razmisliti tudi o uvedbi zdravljenja s kortikosteroidi v odmerku, ki ustreza 1 do 2 mg/kg/dan metilprednizolona.
corticosteroids at a dose of 1 to 2 mg/kg/day methylprednisolone equivalents should also be considered if acute inflammation of the pituitary gland is suspected.

poleg tega je treba pol ure pred injiciranjem zdravila glybera uporabiti intravenski bolus z 1 mg/kg metilprednizolona (glejte poglavje 4.4).
in addition, half an hour prior to glybera injection an intravenous bolus of 1mg/kg of methylprednisolone should be administered (see section 4.4).

v primeru driske ali kolitisa stopnje 3 je treba zdravljenje z nivolumabom v monoterapiji zadržati in uvesti zdravljenje s kortikosteroidi v odmerku, ki ustreza 1 do 2 mg/kg/dan metilprednizolona.
nivolumab monotherapy should be withheld for grade 3 diarrhoea or colitis, and corticosteroids initiated at a dose of 1 to 2 mg/kg/day methylprednisolone equivalents.

metilprednizolon: Študije medsebojnega delovanja aprepitanta 165 mg in metilprednizolona niso bile izvedene, vendar pa je pri uporabi zdravila emend 165 mg in metilprednizolona treba upoštevati sledečo študijo z uporabo aprepitanta po shemi 125 mg/80 mg.
methylprednisolone: interaction studies with aprepitant 165 mg and methylprednisolone have not been conducted; however, the following study with the aprepitant 125 mg/80 mg regimen should be considered when using emend 165 mg with methylprednisolone.

v kliničnih študijah lasofoksifen ni spremenil presnove dekstrometorfana (substrat cyp2d6) in klorzoksazona (substrat cyp2e1) niti farmakokinetike varfarina (substrat cyp2c9), metilprednizolona (substrat cyp3a4) ali digoksina (substrat p-glikoproteina mdr1).
in clinical studies, lasofoxifene did not alter the metabolism of dextromethorphan (cyp2d6 substrate) and chlorzoxazone (cyp2e1 substrate) or the pharmacokinetics of warfarin (cyp2c9 substrate), methylprednisolone (cyp3a4 substrate) or digoxin (mdr1 p-glycoprotein substrate).