検索ワード: fostervækst (デンマーク語 - 英語)

forsinket fostervækst var tydelig i dyreforsøg med pioglitazon.
foetal growth restriction was apparent in animal studies with pioglitazone.

dette reducerer tilgængeligheden af metaboliske substrater til fostervækst.
this was attributable to the action of pioglitazone in diminishing the maternal hyperinsulinaemia and increased insulin resistance that occurs during pregnancy thereby reducing the availability of metabolic substrates for foetal growth.

dyrestudier har vist reproduktionstoksicitet (embryoletalitet, nedsat fostervækst og neonatal død, se pkt.
studies in animals have shown reproductive toxicity (embryolethality, reduced foetal growth, and neonatal death, see section 5.3).

dette skyldtes, at pioglitazon mindskede den maternale hyperinsulinæmi og øgede insulinresistensen, som optræder under graviditet og derved reducerer tilgængeligheden af metaboliske substrater til fostervækst.
this was attributable to the action of pioglitazone in diminishing the maternal hyperinsulinaemia and increased insulin resistance that occurs during pregnancy thereby reducing the availability of metabolic substrates for foetal growth.

den forsinkede fostervækst skyldtes, at pioglitazon mindskede den maternale hyperinsulinæmi og en øget insulinresistens, som optræder under drægtighed.dette reducerer tilgængeligheden af metaboliske substrater til fostervækst.
this was attributable to the action of pioglitazone in diminishing the maternal hyperinsulinaemia and increased insulin resistance that occurs during pregnancy thereby reducing the availability of metabolic substrates for foetal growth.

den fysiologiske måde hvorpå den nødvendige calcium til fostervækst opnås, omfatter øget effektivitet i optagelsen med kosten og mobilisering al'calcium fra moderens knogler '4.
the physiological way of obtaining the calcium required for fetal growth includes an increased efficiency of dietary absorption and the mobilization of calcium from maternal bone14.

det teratogene potentiale hos kaniner kunne ikke vurderes fuldstændigt, dog blev der observeret øget embryo-føtal dødelighed ved doser på 1,5 mg/kg og højere, og nedsættelse af levedygtighed hos fostre såvel som hæmmet fostervækst ved 5 mg/kg.
the teratogenic potential in rabbits could not be fully assessed, however an increased embryo-foetal mortality was seen at doses of 1.5 mg/kg and higher, and a decrease in viable foetuses as well as foetal growth retardation was seen at 5 mg/kg.