検索ワード: hypospadi (デンマーク語 - 英語)

hypospadi
hypospadias

intranaviculær hypospadi
intravicular hypospadia

chochokas operation for hypospadi
chochodka operation

rattliff's operation for hypospadi
rattliff operation

hypospadi er en forholdsvis almindelig misdannelse.
hypospadias is a relatively common malformation.

for loratadin under graviditeten øger risikoen for hypospadi.
pregnancy increases the risk of hypospadia.

cpmp/ 4060/ 03 hypospadi de til dato udførte undersøgelser medicinska födelseregistret
cpmp/ 4060/ 03 hypospadias studies conducted to date swedish medical birth registry (smbr)

dieffenbach-duplay-kroenlein-byars-thierschs operation for hypospadi
dieffenbach-duplay-kroenlein-byars-thiersch operation

de fremlagte oplysninger viser derfor, at hypospadi ikke er blevet indberettet spontant som en lægemiddelbivirkning.
hence, the data presented show that hypospadias have not been spontaneously reported as an adverse drug reaction.

ud af 2 780 eksponerede graviditeter var der i alt 15 tilfælde af hypospadi mod en forventet forekomst på 6- 7 tilfælde.
among 2,780 exposed pregnancies there were in total 15 cases of hypospadias vs. the expected incidence of 6-7 cases.

cpmp konkluderede, at medicinska födelseregistret giver et robust signal om, at eksponering for loratadin under graviditeten øger risikoen for hypospadi.
the cpmp concluded that the smbr provides a robust signal that loratadine exposure during pregnancy increases the risk of hypospadia.

i en analyse af data fra medicinska födelseregistret i november 2001 fandtes 15 tilfælde af hypospadi ud af 2 780 loratadin- eksponerede graviditeter.
in an analysis of data from the smbr in november 2001, 15 cases of hypospadias were identified among 2,780 loratadine-exposed pregnancies.

läkemedelsverket konkluderede på grundlag af disse oplysninger, at det ikke kan udelukkes, at brug af loratadin i første trimester kan være forbundet med øget risiko for hypospadi.
based on these data, the mpa considered that it could not be excluded that the use of loratadine during the first trimester of pregnancy may be associated with an increased risk of hypospadia.

i disse indberetninger indgår de 15 tilfælde af hypospadi fra medicinska födelseregistret samt 8 spontane indberetninger, der er modtaget efter indledning af artikel 31- proceduren for indbragte sager.
these reports include the 15 hypospadias cases from the smbr, and 8 spontaneous reports that were received following the initiation of the article 31 referral procedure.

prækliniske undersøgelser udvikling af genitalia externa masculina og vigtigheden af androgener cpmp konkluderede, at antiandrogen aktivitet på nuværende tidspunkt er den eneste kendte ikke - genetiske mekanisme for fremkaldelse af hypospadi.
preclinical studies external male genitalia development and importance of androgens the cpmp concluded that antiandrogenic activity is the only currently known non-genetic mechanism for induction of hypospadias.

antiandrogene endepunkter i loratadin- undersøgelser cpmp vurderede en række parametre, der er relevante for antiandrogent potentiale, herunder hypospadi, i undersøgelser af reproduktiv toksicitet af loratadin.
antiandrogenic endpoints in loratadine studies the cpmp assessed a number of parameters addressing antiandrogenic potential, including hypospadias in the loratadine reproductive toxicity studies.

9/20 hypospadier på grundlag af den `naturlige'baggrundsincidens.de fremlagte oplysninger viser derfor, at hypospadi ikke er blevet indberettet spontant som en lægemiddelbivirkning.
9/21 the information available in the medical literature does not indicate an increased risk of congenital malformation with loratadine use.

hvis spontan indberetning giver pålidelige oplysninger, skulle man have forventet et antal hypospadier på grundlag af den ‘ naturlige ’ baggrundsincidens.
if spontaneous reporting would provide reliable data, a number of hypospadias would have been expected based on the ‘ natural’ background incidence.