検索ワード: dehydrogeneringen (ノルウェー語 - 英語)

basert på in vitro-forsøk er cyp3a4 og cyp2d6 enzymer ansvarlige for dehydrogeneringen og hydroksyleringen av aripiprazol, mens n- dealkyleringen er katalysert av cyp3a4.
based on in vitro studies, cyp3a4 and cyp2d6 enzymes are responsible for dehydrogenation and hydroxylation of aripiprazole, and n-dealkylation is catalysed by cyp3a4.

aripiprazol har en omfattende metabolisering i lever, hovedsakelig via tre biotransformasjonsveier: dehydrogenering, hydroksylering og n-dealkylering.
aripiprazole is extensively metabolised by the liver primarily by three biotransformation pathways: dehydrogenation, hydroxylation, and n-dealkylation.