検索ワード: mikrotubuli (マルタ語 - 英語)

ir-rabta ta’ docetaxel mal-mikrotubuli ma jibdilx in-numru tal- protofilamenti.
the binding of docetaxel to microtubules does not alter the number of protofilaments.

eribulin mesilate hu inibitur tad-dinamika tal-mikrotubuli li jappartjeni għall-klassi halichondrin ta’ mediċini antineoplastiċi.
eribulin mesilate is a microtubule dynamics inhibitor belonging to the halichondrin class of antineoplastic agents.

il- mikrotubuli huma essenzjali għall- funzjoni mitotika vitali u għall- funzjoni ċellulari ta ’ bejn il- fażijiet.
docetaxel has been shown in vitro to disrupt the microtubular network in cells which is essential for vital mitotic and interphase cellular functions.

dan iwassal għall-istabilizzazzjoni tal-mikrotubuli li jwassal għall- inibizzjoni tal-funzjonijiet ċellulari mitotiċi u tal-interfażi.
this leads to the stabilisation of microtubules, which results in the inhibition of mitotic and interphase cellular functions.

barra dan, tossiċità ta’ maytansine fuq l-iżvilupp kienet identifikata fi studji mhux kliniċi li jissuġġerixxu li dm1, il-komponent maytansinoid ċitotossiku li jinibixxi l-mikrotubuli ta’ trastuzumab emtansine, b’mod simili se jkun teratoġeniku u potenzjalment embrijotossiku.
in addition, developmental toxicity of maytansine has been identified in non-clinical studies which suggests that dm1, the microtubule-inhibiting cytotoxic maytansinoid component of trastuzumab emtansine, will be similarly teratogenic and potentially embryotoxic.