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the polyglutamate forms are retained in cells and are even more potent inhibitors of ts and garft.
poliglutamatni oblici ostaju u stanici i još potentnije inhibiraju ts i garft.
最終更新: 2017-04-26
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once in the cell, pemetrexed is rapidly and efficiently converted to polyglutamate forms by the enzyme folylpolyglutamate synthetase.
kad uđe u stanicu, pemetreksed se pod utjecajem enzima folilpoliglutamat sintetaze brzo i učinkovito pretvara u poliglutamatne oblike.
最終更新: 2017-04-26
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upon being distributed into body tissues, high concentrations particularly in liver, kidneys and spleen in form of polyglutamates can be found, which can be retained for weeks or months.
nakon distribucije u tjelesna tkiva mogu se pronaći visoke koncentracije, osobito u jetri, bubrezima i slezeni, u obliku poligutamata koji se tamo mogu zadržati tjednima ili mjesecima.
最終更新: 2017-04-26
使用頻度: 1
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