検索ワード: debrisoquine (英語 - マルタ語)

administration of pegasys 180 micrograms once weekly for 4 weeks in healthy male subjects did not show any effect on mephenytoin, dapsone, debrisoquine and tolbutamide pharmacokinetics profiles, suggesting that pegasys has no effect on in vivo metabolic activity of cytochrome p450 3a4, 2c9, 2c19 and 2d6 isozymes.
għoti ta’ pegasys 180 mikrogramma darba fil-ġimgħa għal 4 ġimgħat f’irġiel f’saħħithom ma wera l- ebda effett fuq il-profili farmakokinetiċi ta’ mephenytoin, dapsone, debrisoquine u tolbutamide, li jissuġġerixxi li pegasys m’għandu l-ebda effett fuq l-attività metabolika in vivo tal-isożimi 3a4, 2c9, 2c19 u 2d6 taċ-ċitokromju p450.