검색어: ekstramedullari (몰타어 - 영어)

l-ebda xhieda ta’ ċelluli primittivi ċirkulanti jew mard ekstramedullari
no evidence of circulating blasts or extramedullary disease

rikaduta kienet definita bħala irkadar ematoloġiku (blasts fil-mudullun akbar minn 5% wara cr) jew rikaduta ekstramedullari.
relapse was defined as haematological relapse (blasts in bone marrow greater than 5% following cr) or an extramedullary relapse.

tagħrif ta’ qabel l-użu kliniku miġbur minn studji konvenzjonali fuq l-effett tossiku minn dożi riptetuti, ikkonferma l-effetti mistennija, fosthom żjidiet fl-għadd ta’ lewkoċiti, iperplasija majelojde fil-mudullun, ematopojesi ekstramedullari u tkabbir tal-milza.
preclinical data from conventional studies of repeated dose toxicity revealed the expected pharmacological effects including increases in leukocyte count, myeloid hyperplasia in bone marrow, extramedullary haematopoiesis and splenic enlargement.