검색어: biotransformed (영어 - 스웨덴어)

valsartan is not biotransformed to a high extent as only about 20% of dose is recovered as metabolites.
39 valsartan biotransformeras inte i så stor utsträckning, eftersom endast ca 20% av dosen återfinns som metaboliter.

lansoprazole is a racemate of two active enantiomers that are biotransformed into the active form in the acidic environment of the parietal cells.
lansoprazol är ett racemat av två aktiva enantiomerer, som metaboliseras till den aktiva formen i parietalcellernas sura miljö.

bimatoprost is biotransformed by any of multiple enzymes and pathways, and no effects on hepatic drug metabolising enzymes were observed in preclinical studies.
i prekliniska studier har inga effekter observerats på de enzymsystem i levern som metaboliserar läkemedel.

in vivo studies in humans and in vitro studies with human liver microsomes have shown that nevirapine is extensively biotransformed via cytochrome p450 (oxidative) metabolism to several hydroxylated metabolites.
in vivo- studier hos människa och in vitro- studier av humana levermikrosomer har visat att nevirapin genomgår en omfattande biotransformation via cytokrom p450- katalyserad (oxidativ) metabolism till flera hydroxylerade metaboliter.

the primary pathway involves a cytosolic nadp+-linked enzyme, ghb dehydrogenase, that catalyses the conversion of sodium oxybate to succinic semialdehyde, which is then biotransformed to succinic acid by the enzyme succinic semialdehyde dehydrogenase.
i den primära elimineringsvägen är ett cytosoliskt nadp+- förbundet enzym, ghb- dehydrogenas inblandat vilket katalyserar omvandlingen av natriumoxybat till succinylsemialdehyddehydrogenas.