검색어: hydroxylated (영어 - 슬로베니아어)

lanolin, hydroxylated
lanolin, hidroksiliran

glycerides, milk, hydroxylated
gliceridi, mleko, hidroksilirani

there are several hydroxylated metabolites of quinidine.
obstaja več hidroksiliranih metabolitov kinidina.

unchanged emodepside and hydroxylated derivatives are the major excretion products.
nespremenjeni emodepsid in hidroksilirani derivati so glavni presnovki.

(polyethylene terephthalate, hydroxylated polybutadiene, pyromellitic anhydride) copolymer
kopolimer (polietilen tereftalata, hidroksiliranega polibutadiena, piromelitičnega anhidrida)

ketoconazole and erythromycin significantly inhibited the formation of nevirapine hydroxylated metabolites.
ketokonazol in eritromicin sta nastajanje nevirapinovih hidroksiliranih presnovkov pomembno zavirala.

ethinyl estradiol is also metabolised to various hydroxylated products and their glucuronide and sulfate conjugates.
etinilestradiol se prav tako presnovi v različne hidroksilirane produkte in njihove glukuronidne in sulfatne konjugate.

oxidative metabolism catalysed by cyp3a4 and cyp2c8 leads to the formation of hydroxylated and dealkylated products.
oksidativna presnova, ki jo katalizirata cyp3a4 in cyp2c8, ima za posledico nastanek hidroksiliranih in dealkiliranih snovi.

greater than 80 % of the radioactivity in urine was made up of glucuronide conjugates of hydroxylated metabolites.
več kot 80 % radioaktivne snovi v seču so sestavljali glukuronidni konjugati hidroksiliranih presnovkov.

osaterone acetate is converted to its main, 15-hydroxylated metabolite, which is also pharmacologically active.
osateronijev acetat se pretvori v glavni 15β-hidroksiliran metabolit, ki je prav tako farmakološko aktiven.

the major metabolites, hydroxylated and demethylated agomelatine, are not active and are rapidly conjugated and eliminated in the urine.
poglavitna presnovka, hidroksilirani in demetilirani agomelatin, nista aktivna ter se hitro konjugirata in odstranita iz telesa z urinom.

the formation of these hydroxylated metabolites is catalysed by cyp2c8, cyp3a4, and both cyp2c8 and cyp3a4 isoenzymes, respectively.
formacijo teh hidroksiliranih metabolitov katalizirajo izoencimi cyp2c8, -cyp3a4 ter oba -cyp2c8 in -cyp3a4.

hepatic metabolism of norelgestromin occurs and metabolites include norgestrel, which is largely bound to shbg, and various hydroxylated and conjugated metabolites.
norelgestromin se presnavlja v jetrih, metaboliti pa vključujejo norgestrel (ki se v veliki meri veže na shbg) in različne hidroksilirane in konjugirane metabolite.

based on in vitro studies, saquinavir is rapidly metabolised to a range of mono- and di-hydroxylated inactive compounds.
na podlagi in vitro študij se sakvinavir hitro presnavlja v razpon mono- in dihidroksiliranih neaktivnih spojin.

three metabolites of lasofoxifene were detected in plasma: the direct glucuronide conjugate, the glucuronide of a hydroxylated metabolite, and the methylated catechol.
v plazmi so odkrili tri presnovke lasofoksifena: direktni glukuronidni konjugat, glukuronid hidroksiliranega presnovka in metilirani katehol.

a hydroxylated metabolite of valdecoxib (via the cyp pathway) has been identified in human plasma that is active as a cox-2 inhibitor.
v človeški plazmi je bil ugotovljen (po poti cyp) hidroksilirani presnovek valdekoksiba, ki deluje kot zaviralec cox-2.

biotransformation: studies in humans and in vitro studies using human liver microsomes have demonstrated that efavirenz is principally metabolised by the cytochrome p450 system to hydroxylated metabolites with subsequent glucuronidation of these hydroxylated metabolites.
presnova: študije pri ljudeh in študije in vitro z uporabo človeških jetrnih mikrosomov so pokazale, da se efavirenz presnavlja predvsem s sistemom citokroma p450, in sicer v hidroksilirane presnovke, z nadaljnjo glukuronidacijo teh hidroksiliranih presnovkov.

in vivo studies in humans and in vitro studies with human liver microsomes have shown that nevirapine is extensively biotransformed via cytochrome p450 (oxidative) metabolism to several hydroxylated metabolites.
raziskave in vitro s človeškimi jetrnimi mikrosomi

the major part is hydrogenated or hydroxylated in humans, the major metabolites being hydroxy-6-dexamethasone and dihydro-20-dexamethasone.
večji del se pri ljudeh hidrogenira ali hidroksilira, pri čemer sta glavna presnovka hidroksi-6-deksametazon in dihidro-20- deksametazon.

commission directive 2003/104/ec of 12 november 2003 authorising isopropyl ester of the hydroxylated analogue of methionine(5) is to be incorporated into the agreement.
direktivo komisije 2003/104/es z dne 11. novembra 2003, s katero se dovoljuje izopropil ester hidroksiliranega analognega metionina [5], je treba vključiti v sporazum.