검색어: tizanidine (영어 - 슬로베니아어)

tizanidine
tizanidin

tizanidine, a muscle relaxant
tizanidin, mišični relaksant,

concurrent administration of ciprofloxacin and tizanidine
sočasni uporabi ciprofloksacina in tizanidina.

co-administration of ciprofloxacin and tizanidine is contra-indicated.
sočasna uporaba ciprofloksacina in tizanidina je kontraindicirana.

concomitant administration of ciprofloxacin and tizanidine (see section 4.5).
sočasna uporaba ciprofloksacina in tizanidina (glejte poglavje 4. 5)

increased serum tizanidine concentration is associated with a potentiated hypotensive and sedative effect.
z zvišanjem serumske koncentracije sta bila povezana izrazit hipotenzivni in sedativni učinek.

tizanidine must not be administered together with ciprofloxacin (see section 4.3).
tizanidina se ne sme uporabljati sočasno s ciprofloksacinom (glejte poglavje 4. 3).

in a clinical study with healthy subjects, there was an increase in serum tizanidine concentration (cmax increase:
v klinični študiji se je pri zdravih prostovoljcih, ki so sočasno s tizanidinom prejemali tudi ciprofloksacin zvečala serumska koncentracija tizanidina (zvišanje cmax:

do not take ciprofloxacin bayer together with tizanidine, because this may cause side effects such as low blood pressure and sleepiness (see section 2:
8.

for substances that are predominantly metabolised by cyp1a2 and that have a narrow therapeutic index (e.g. clozapine, tizanidine), the same recommendations apply as for theophylline.
za zdravilne učinkovine, ki se pretežno presnavljajo s cyp1a2 in imajo ozek terapevtski indeks, (na primer klozapin in tizanidin) veljajo enaka priporočila kot za teofilin.

117 cytochrome p450 ciprofloxacin inhibits cyp1a2 and thus may cause increased serum concentration of concomitantly administered substances metabolised by this enzyme (e. g. theophylline, clozapine, ropinirole, tizanidine).
118 citokrom p450 ciprofloksacin zavira encimski sistem cyp1a2, kar lahko povzroči zvišanje serumskih koncentracij sočasno danih zdravil, ki se presnavljajo s pomočjo tega encima (npr. teofilin, klozapin, ropinirol, tizanidin).