Je was op zoek naar: monophosphatmetabolit (Deens - Engels)

nelarabin demethyleres hurtigt af adenosindeaminase (ada) til ara-g, som derefter phosphoryleres intracellulært af deoxyguanosinkinase og deoxycytidinkinase til dets 5’-monophosphatmetabolit.
nelarabine is rapidly demethylated by adenosine deaminase (ada) to ara-g and then phosphorylated intracellularly by deoxyguanosine kinase and deoxycytidine kinase to its 5’-monophosphate metabolite.

monophosphatmetabolitten omdannes derefter til den aktive 5’-triphosphat fra ara-gtp.
the monophosphate metabolite is subsequently converted to the active 5’-triphosphate from, ara-gtp.