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similar to the reported effects on the steroid and th systems the observed effects on glucose homeostasis/ insulin levels are suggestive of the endocrine disruptive potential of bde-209.
与已经报告的对类固醇和th系统的作用类似,观察到对葡萄糖稳态/胰岛素水平有影响,表明bde-209有可能干扰内分泌。
the interleukin-6 receptor antagonist was approved by the fda based on retrospective case studies for treatment of steroid refractory cytokine release syndrome induced by a different cause, car t cell therapy, in 2017.
2017 年,在回顾性病例研究的支持下,fda 批准使用白细胞介素 6 受体拮抗剂治疗由其他原因引起的类固醇难治性细胞因子释放综合征,即 car t 细胞疗法。
chemicals thought to play a major role in this relationship include naturally occurring steroid and synthetic hormones, organic and inorganic pesticides, pcbs and dioxins (swan and others, 1997).
在此方面发挥重要作用的化学剂包括天然的类固醇及合成荷尔蒙、有机和无机杀虫剂、多氯联苯以及二氧杂芑(swan等,1997年)。