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de este modo, el campo de células se subdivide en diferentes tipos de acuerdo con su posición relativa a la fuente del morfógeno.
in this way, the field of cells is subdivided into different types according to their position relative to the source of the morphogen.
el morfógeno provee la información espacial formando un gradiente de concentración que subdivide un campo de células induciendo o manteniendo diferentes genes clave en distintos umbrales de concentración.
the morphogen provides spatial information by forming a concentration gradient that subdivides a field of cells by inducing or maintaining the expression of different target genes at distinct concentration thresholds.
un morfógeno es una sustancia que gobierna el patrón del desarrollo tisular y, en particular, las posiciones de varios tipos de células especializadas dentro de un tejido.
a morphogen is a substance governing the pattern of tissue development in the process of morphogenesis, and the positions of the various specialized cell types within a tissue.
sonic hedgehog es un ejemplo canónico de un morfógeno tal como fue definido por el modelo de la bandera francesa de lewis wolpert: una molécula que difunde para formar un gradiente de concentración y tiene diferentes efectos en las células del embrión en desarrollo dependiendo de su concentración.
sonic hedgehog is the best established example of a morphogen as defined by lewis wolpert's french flag model—a molecule that diffuses to form a concentration gradient and has different effects on the cells of the developing embryo depending on its concentration.
== véase también ==* plan corporal* morfógeno* operón* biología sistémica== referencias ==== enlaces externos ==* gene regulatory networks — short introduction* open source web service for grn analysis* bib: yeast biological interaction browser* graphical gaussian models for genome data — inference of gene association networks with ggms* a bibliography on learning causal networks of gene interactions - regularly updated, contains hundreds of links to papers from bioinformatics, statistics, machine learning.
== see also ==* body plan* cis-regulatory module* genenetwork (database)* morphogen* operon* synexpression* systems biology* weighted gene co-expression network analysis== notes ==== references ==== external links ==* gene regulatory networks — short introduction* open source web service for grn analysis* bib: yeast biological interaction browser* graphical gaussian models for genome data — inference of gene association networks with ggms* a bibliography on learning causal networks of gene interactions - regularly updated, contains hundreds of links to papers from bioinformatics, statistics, machine learning.