Você procurou por: cyclopropylbenzamide (Francês - Alemão)

composé selon la revendication 1, choisi parmi : le n-(2-{[(2s)-3-(5-chloro-1'h,3h-spiro[1-benzofuran-2,4'-pipéridin]-1'-yl)-2-hydroxypropyl]oxy}phényl)-acétamide, le n-(2-{[(2s)-3-(5-chloro-1'h,3h-spiro[1-benzofuran-2,4'-pipéridin]-1'-yl)-2-hydroxypropyl]oxy}-4-fluorophényl)acétamide, le n-(2-{[(2s)-3-(5-chloro-1'h,3h-spiro[1-benzofuran-2,4'-pipéridin]-1'-yl)-2-hydroxypropyl]oxy}-4-méthoxyphényl)acétamide, le n-(2-{[(2s)-3-(5-chloro-1'h,3h-spiro[1-benzofuran-2,4'-pipéridin]-1'-yl)-2-hydroxypropyl]oxy}-4-hydroxyphényl)acétamide, le n-[2-{[(2s)-3-(5-chloro-1'h,3h-spiro[1-benzofuran-2,4'-pipéridin]-1'-yl)-2-hydroxypropyl]oxy}-5-(trifluorométhyl)phényl]acétamide, le 2-{[(2s)-3-(5-chloro-1'h,3h-spiro[1-benzofuran-2,4'-pipéridin]-1'-yl)-2-hydroxypropyl]oxy}-n-cyclopropylbenzamide, le 2-{[(2s)-3-(5-chloro-1'h,3h-spiro[1-benzofuran-2,4'-pipéridin]-1'-yl)-2-hydroxypropyl]oxy}-n-cyclopropyl-4-fluorobenzamide, le 2-{[(2s)-3-(5-chloro-1'h,3h-spiro[1-benzofuran-2,4'-pipéridin]-1'-yl)-2-hydroxypropyl]oxy}-n-cyclopropyl-4-méthoxybenzamide, le trifluoracétate de n-(2-{[(2s)-3-(5-chloro-1'h,3h-spiro[1-benzofuran-2,4'-pipéridin]-1'-yl)-2-hydroxy-2-méthylpropyl]oxy}-4-hydroxyphényl)acétamide, le n-(5-chloro-2-{[(2s)-3-(6-chloro-1'h,3h-spiro[2-benzofuran-1,4'-pipéridin]-1'-yl)-2-hydroxypropyl]oxy}phényl)acétamide, le n-(2-{[(2s)-3-(6-chloro-1'h,3h-spiro[2-benzofuran-1,4'-pipéridin]-1'-yl)-2-hydroxypropyl]oxy}-4-fluorophényl)acétamide, le n-(2-{[(2s)-3-(6-chloro-1'h,3h-spiro[2-benzofuran-1,4'-pipéridin]-1'-yl)-2-hydroxypropyl]oxy}phényl)-acétamide, le n-(2-{[(2s)-3-(6-chloro-1'h,3h-spiro[2-benzofuran-1,4'-pipéridin]-1'-yl)-2-hydroxypropyl]oxy}-4-méthoxyphényl)acétamide, le 2-{[(2s)-3-(6-chloro-1'h,3h-spiro[2-benzofuran-1,4'-pipéridin]-1'-yl)-2-hydroxypropyl]oxy}-n-cyclopropyl-4-fluorobenzamide, le n-(2-{[(2s)-3-(5-fluoro-1'h,3h-spiro[2-benzofuran-1,4'-pipéridin]-1'-yl)-2-hydroxypropyl]phényl)-acétamide, le n-cyclopropyl-2-{[(2s)-2-hydroxy-3-(1'h,3h-spiro[2-benzofuran-1,4'-pipéridin]-1'-yl)propyl]oxy}benzamide, le n-(4-chloro-2-{[(2s)-2-hydroxy-3-(1'h,3h-spiro[2-benzofuran-1,4'-pipéridin]-1'-yl)propyl]oxy}phényl)-acétamide, le n-(5-chloro-2-{[(2s)-2-hydroxy-3-(1'h,3h-spiro[2-benzofuran-1,4'-pipéridin]-1'-yl)propyl]oxy}phényl)-acétamide, le n-(2-{[(2s)-2-hydroxy-2-méthyl-3-(1'h,3h-spiro[2-benzofuran-1,4'-pipéridin]-1'-yl)propyl]oxy}-4-méthoxyphényl)acétamide, le n-[2-{[(2s)-2-hydroxy-3-(1'h,3h-spiro[2-benzofuran-1,4'-pipéridin]-1'-yl)propyl]oxy}-5-(trifluorométhyl)-phényl]acétamide, le n-(2-{[(2s)-2-hydroxy-3-(2-méthyl-1'h-spiro[indène-1,4'-pipéridin]-1'-yl)propyl]oxy}phényl)acétamide, le n-(2-{[(2s)-3-(2,3-dihydro-1'h-spiro[indène-1,4'-pipéridin]-1'-yl)-2-hydroxypropyl]oxy}phényl)acétamide, le 2-{[(2s)-3-(5-chloro-1'h,3h-spiro[1-benzofuran-2,4'-pipéridin]-1'-yl)-2-hydroxypropyl]oxy}-n-cyclopropyl-4-hydroxybenzamide, 2-{[(2s)-3-(5-chloro-1'h,3h-spiro[1-benzofuran-2,4'-pipéridin]-1'-yl)-2-hydroxy-2-méthylpropyl]oxy}-n-cyclopropyl-4-hydroxybenzamide, le 2-{[(2s)-3-(5-chloro-1'h,3h-spiro[1-benzofuran-2,4'-pipéridin]-1'-yl)-2-hydroxy-2-méthylpropyl]oxy}-4-hydroxy-n-méthylbenzamide(trifluoracétate), le 2-{[(2s)-3-(5-chloro-1'h,3h-spiro[1-benzofuran-2,4'-pipéridin]-1'-yl)-2-hydroxy]oxy}-4-hydroxy-n-méthylbenzamide, le trifluoracétate de n-(2-{[(2s)-3-(5-chloro-1'h-spiro[1,3-benzodioxole-2,4'-pipéridin]-1'-yl)-2-hydroxypropyl]oxy}-4-hydroxyphényl)acétamide, le trifluoracétate de n-(2-{[(2s)-3-(5-chloro-1'h-spiro[1,3-benzodioxole-2,4'-pipéridin]-1'-yl)-2-hydroxy-2-méthylpropyl]oxy}-4-hydroxyphényl)acétamide, le trifluoracétate de n-(4-hydroxy-2-{[(2s)-2-hydroxy-3-(1'h-spiro[1,3-benzodioxole-2,4'-pipéridin]-1'-yl)-propyl]oxy}phényl)acétamide, le trifluoracétate de n-(4-hydroxy-2-{[(2s)-2-hydroxy-2-méthyl-3-(1'h-spiro[1,3-benzodioxole-2,4'-pipéridin]-1'-yl)propyl]oxy}phényl)acétamide, le n-(2-{[(2s)-3-(5-chloro-1'h,3h-spiro[2-benzofuran-1,4'-pipéridin]-1'-yl)-2-hydroxypropyl]oxy}-4-hydroxyphényl)acétamide, le n-(2-{[(2s)-3-(5-chloro-1'h,3h-spiro[2-benzofuran-1,4'-pipéridin]-1'-yl)-2-hydroxypropyl]oxy}phényl)-acétamide, le 2-{[(2s)-3-(5-chloro-1'h,3h-spiro[2-benzofuran-1,4'-pipéridin]-1'-yl)-2-hydroxypropyl]oxy}-4-hydroxy-n-méthylbenzamide, le 2-{[(2s)-3-(5-chloro-1' h ,3 h -spiro[2-benzofuran-1,4'-pipéridin]-1'-yl)-2-hydroxy-2-méthoxypropyl]oxy}-n-cyclopropyl-4-hydroxybenzamide, le 2-{[(2s)-3-(5-chloro-1'h,3h-spiro[1-benzofuran-2,4'-pipéridin]-1'-yl)-2-hydroxypropyl]oxy}-4-hydroxy-n-(2-hydroxyéthyl)benzamide, le n-(2-aminoéthyl)-2-{[(2s)-3-(5-chloro-1'h,3h-spiro[1-benzofuran-2,4'-pipéridin]-1'-yl)-2-hydroxypropyl]oxy}-4-hydroxybenzamide, le 2-{[(2s)-3-(5-fluoro-1'h,3h-spiro[1-benzofuran-2,4'-pipéridin]-1'-yl)-2-hydroxypropyl]oxy}-4-hydroxy-n-méthylbenzamide, le n-(2-{[(2s)-3-(5-fluoro-1'h,3h-spiro[1-benzofuran-2,4'-pipéridin]-1'-yl)-2-hydroxypropyl]oxy}-4-hydroxyphényl)acétamide, le n-(2-{[(2s)-3-(5-fluoro-1'h,3h-spiro[1-benzofuran-2,4'-pipéridin]-1'-yl)-2-hydroxypropyl]oxy}phényl)-acétamide, le n-[2-({(2s)-3-[(2s)-5-chloro-1'h,3h-spiro[1-benzofuran-2,3'-pyrrolidin]-1'-yl]-2-hydroxypropyl}oxy)phényl]acétamide, le n-[2-({(2s)-3-[(2r)-5-chloro-1'h,3h-spiro[1-benzofuran-2,3'-pyrrolidin]-1'-yl]-2-hydroxypropyl}oxy)phényl]acétamide, le n-[2-({(2s)-3-[(2s)-5-chloro-1'h,3h-spiro[1-benzofuran-2,3'-pyrrolidin]-1'-yl]-2-hydroxypropyl}oxy)-4-méthoxyphényl]acétamide, le n-[2-({(2s)-3-[(2r)-5-chloro-1'h,3h-spiro[1-benzofuran-2,3'-pyrrolidin]-1'-yl]-2-hydroxypropyl}oxy)-4-méthoxyphényl]acétamide, le 2-{[(2s)-3-(5-chloro-1'h,3h-spiro[1-benzofuran-2,3'-pyrrolidin]-1'-yl)-2-hydroxypropyl]oxy}-4-hydroxy-n-méthylbenzamide, l'acide 2-{[(2s)-3-(5-chloro-1'h,3h-spiro[1-benzofuran-2,4'-pipéridin]-1'-yl)-2-hydroxypropyl]oxy}-4-hydroxybenzoïque (trifluoracétate), le 3(s)-1-(2-{[(2s)-3-(5-chloro-1'h,3h-spiro[1-benzofuran-2,4'-pipéridin]-1'-yl)-2-hydroxypropyl]oxy}-4-hydroxybenzoyl)pyrrolidin-3-ol, le 3(r)-1-(2-{[(2s)-3-(5-chloro-1'h,3h-spiro[1-benzofuran-2,4'-pipéridin]-1'-yl)-2-hydroxypropyl]oxy}-4-hydroxybenzoyl)pyrrolidin-3-ol, le 3-{[(2s)-3-(5-chloro-1'h,3h-spiro[1-benzofuran-2,4'-pipéridin]-1'-yl)-2-hydroxypropyl]oxy}-4-(morpholin-4-ylcarbonyl)phénol, et les sels pharmaceutiquement acceptables et les solvats d'un quelconque parmi ceux-ci.
verbindungen nach anspruch 1, ausgewählt aus: n -(2-{[(2s)-3-(5-chlor-1' h ,3 h -spiro[1-benzofuran-2,4'-piperidin]-1'-yl)-2-hydroxypropyl]oxy}-phenyl)acetamid, n -(2-{[(2 s )-3-(5-chlor-1' h ,3 h -spiro[1-benzofuran-2,4'-piperidin]-1'-yl)-2-hydroxypropyl]oxy}-4-fluorphenyl)acetamid, n-(2-{[(2s)-3-(5-chlor-1'r,3r-spiro[1-benzofuran-2,4'-piperidin]-1'-yl)-2-hydroxypropyl]oxy}-4-methoxyphenyl)acetamid, n -(2-{[(2s)-3-(5-chlor-1' h ,3 h -spiro[1-benzofuran-2,4'-piperidin]-1'-yl)-2-hydroxypropyl]oxy}-4-hydroxyphenyl)acetamid, n -(2-{[(2s)-3-(5-chlor-1' h ,3 h -spiro[1-benzofuran-2,4'-piperidin]-1'-yl)-2-hydroxypropyl]oxy}-5-(trifluormethyl)phenyl)acetamid, 2-{[(2s)-3-(5-chlor-1' h ,3 h -spiro[1-benzofuran-2,4'-piperidin]-1'-yl)-2-hydroxypropyl]oxy}-n-cyclopropylbenzamid, 2-{[(2s)-3-(5-chlor-1' h ,3 h -spiro[1-benzofuran-2,4'-piperidin]-1'-yl)-2-hydroxypropyl]oxy}-n-cyclopropyl-4-fluorbenzamid, 2-{[(2s)-3-(5-chlor-1' h ,3 h -spiro[1-benzofuran-2,4'-piperidin]-1'-yl)-2-hydroxypropyl]oxy}-n-cyclopropyl-4-methoxybenzamid, n -(2-{[(2s)-3-(5-chlor-1' h ,3 h -spiro[1-benzofuran-2,4'-piperidin]-1'-yl)-2-hydroxy-2-methylpropyl]oxy}-4-hydroxyphenyl)acetamidtrifluoracetat, n -(5-chlor-2-{[(2s)-3-(6-chlor-1' h ,3 h -spiro[2-benzofuran-1,4'-piperidin]-1'-yl)-2-hydroxypropyl]oxy}phenyl)acetamid, n-(2-{[(2s)-3-(6-chlor-1' h ,3 h -spiro[2-benzofuran-1,4'-piperidin]-1'-yl)-2-hydroxypropyl]oxy}-4-fluorphenyl)acetamid, n -(2-{[(2s)-3-(6-chlor-1' h ,3 h -spiro[2-benzofuran-1,4'-piperidin]-1'-yl)-2-hydroxypropyl]oxy}phenyl)acetamid, n -(2-{[(2s)-3-(6-chlor-1' h ,3 h -spiro[2-benzofuran-1,4'-piperidin]-1'-yl)-2-hydroxypropyl]oxy}-4-methoxyphenyl)acetamid, 2-{[(2s)-3-(6-chlor-1' h ,3 h -spiro[2-benzofuran-1,4'-piperidin]-1'-yl)-2-hydroxypropyl]oxy}-n-cyclopropyl-4-fluorbenzamid, n-(2-{[(2s)-3-(5-fluor-1' h ,3 h -spiro[2-benzofuran-1,4'-piperidin]-1'-yl)-2-hydroxypropyl]phenyl)acetamid, n-cyclopropyl-2-{[(2s)-2-hydroxy-3-(1' h ,3 h- spiro[2-benzofuran-1,4'-piperidin]-1'-yl)propyl]oxy}benzamid, n -(4-chlor-2-{[(2s)-2-hydroxy-3-(1' h ,3 h -spiro[2-benzofuran-1,4'-piperidin]-1'-yl)propyl]oxy}phenyl)acetamid, n -(5-chlor-2-{[(2s)-2-hydroxy-3-(1' h ,3 h -spiro[2-benzofuran-1,4'-piperidin]-1'-yl)propyl]oxy}phenyl)acetamid, n -(2-{[(2s)-2-hydroxy-2-methyl-3-(1' h ,3 h -spiro[2-benzofuran-1,4'-piperidin]-1'-yl)propyl]oxy}-4-methoxyphenyl)acetamid, n -[2-{[(2s)-2-hydroxy-3-(1' h ,3 h -spiro[2-benzofuran-1,4'-piperidin]-1'-yl)propyl]oxy}-5-(trifluormethyl)phenyl]acetamid, n -(2-{[(2 s )-2-hydroxy-3-(2-methyl-1' h -spiro[inden-1,4'-piperidin]-1'-yl)propyl]oxy}phenyl)acetamid, n -(2-{[(2s)-3-(2,3-dihydro-1' h -spiro[inden-1,4'-piperidin]-1'-yl)-2-hydroxypropyl]oxy}phenyl)acetamid, 2-{[(2 s )-3-(5-chlor-1' h ,3 h -spiro[1-benzofuran-2,4'-piperidin]-1'-yl)-2-hydroxypropyl]oxy}-n-cyclopropyl-4-hydroxybenzamid, 2-{[(2 s )-3-(5-chlor-1' h ,3 h -spiro[1-benzofuran-2,4'-piperidin]-1'-yl)-2-hydroxy-2-methylpropyl]oxy}-n-cyclopropyl-4-hydroxybenzamid, 2-{[(2s)-3-(5-chlor-1' h ,3 h -spiro [1-benzofuran-2,4'-piperidin]-1'-yl)-2-hydroxy-2-methylpropyl]oxy}-4-hydroxy-n-methylbenzamid(trifluoracetat), 2-{[(2s)-3-(5-chlor-1' h ,3 h -spiro[1-benzofuran-2,4'-piperidin]-1'-yl)-2-hydroxy]oxy}-4-hydroxy-n-methylbenzamid, n -(2-{[(2s)-3-(5-chlor-1' h -spiro[1,3-benzodioxol-2,4'-piperidin]-1'-yl)-2-hydroxypropyl]oxy}-4-hydroxyphenyl)acetamidtrifluoracetat, n -(2-{[(2s)-3-(5-chlor-1' h -spiro[1,3-benzodioxol-2,4'-piperidin]-1'-yl)-2-hydroxy-2-methylpropyl]oxy}-4-hydroxyphenyl)acetamidtrifluoracetat, n -(4-hydroxy-2-{[(2s)-2-hydroxy-3-(1' h -spiro[1,3-benzodioxol-2,4'-piperidin]-1'-yl)propyl]oxy}phenyl)acetamidtrifluoracetat, n -(4-hydroxy-2-{[(2s)-2-hydroxy-2-methyl-3-(1' h- spiro[1,3-benzodioxol-2,4'-piperidin]-1'-yl)propyl]oxy}phenyl)acetamidtrifluoracetat, n -(2-{[(2s)-3-(5-chlor-1' h ,3 h -spiro[2-benzofuran-1,4'-piperidin]-1'-yl)-2-hydroxypropyl]oxy}-4-hydroxyphenyl)acetamid, n -(2-{[(2s)-3-(5-chlor-1' h ,3 h -spiro[2-benzofuran-1,4'-piperidin]-1'-yl)-2-hydroxypropyl]oxy}phenyl)acetamid, 2-{[(2s)-3-(5-chlor-1' h ,3 h -spiro [2-benzofuran-1,4'-piperidin]-1'-yl)-2-hydroxypropyl]oxy}-4-hydroxy-n-methylbenzamid, 2-{[(2s)-3-(5-chlor-1' h ,3 h -spiro [2-benzofuran-1,4'-piperidin]-1'-yl)-2-hydroxy-2-methoxypropyl]oxy}-n-cyclopropyl-4-hydroxybenzamid, 2-{[(2s)-3-(5-chlor-1' h ,3 h -spiro[1-benzofuran-2,4'-piperidin]-1'-yl)-2-hydroxypropyl]oxy}-4-hydroxy-n-(2-hydroxyethyl)benzamid, n -(2-aminoethyl)-2-{[(2s)-3-(5-chlor-1' h ,3 h- spiro[1-benzofuran-2,4'-piperidin]-1'-yl)-2-hydroxypropyl]oxy}-4-hydroxybenzamid, 2-{[(2s)-3-(5-fluor-1' h ,3 h -spiro[1-benzofuran-2,4'-piperidin]-1'-yl)-2-hydroxypropyl]oxy}-4-hydroxy- n -methylbenzamid, n -(2-{[(2s)-3-(5-fluor-1' h ,3 h -spiro[1-benzofuran-2,4'-piperidin]-1'-yl)-2-hydroxypropyl]oxy}-4-hydroxyphenyl)acetamid, n -(2-{[(2s)-3-(5-fluor-1' h ,3 h -spiro[1-benzofuran-2,4'-piperidin]-1'-yl)-2-hydroxypropyl]oxy}phenyl)acetamid, n -(2-{[(2s)-3-[(2s)-5-chlor-1' h ,3 h -spiro[1-benzofuran-2,3'-pyrrolidin]-1'-yl]-2-hydroxypropyl}oxy)phenyl]acetamid, n -(2-{[(2s)-3-[(2r)-5-chlor-1' h ,3 h -spiro[1-benzofuran-2,3'-pyrrolidin]-1'-yl]-2-hydroxypropyl}oxy)phenyl]acetamid, n -(2-{[(2s)-3-[(2s)-5-chlor-1' h ,3 h -spiro[1-benzofuran-2,3'-pyrrolidin]-1'-yl]-2-hydroxypropyl}oxy)-4-methoxyphenyl]acetamid, n -(2-{[(2s)-3-[(2r)-5-chlor-1' h ,3 h -spiro[1-benzofuran-2,3'-pyrrolidin]-1'-yl]-2-hydroxypropyl}oxy)-4-methoxyphenyl]acetamid, 2-{[(2s)-3-(5-chlor-1' h ,3 h -spiro [1-benzofuran-2,3'-pyrrolidin]-1'-yl)-2-hydroxypropyl]oxy}-4-hydroxy-n-methoxybenzamid, 2-{[(2s)-3-(5-chlor-1' h ,3 h -spiro[1-benzofuran-2,4'-piperidin]-1'-yl)-2-hydroxypropyl]oxy}-4-hydroxybenzoesäure(trifluoracetat), 3(s)-1-(2-{[(2s)-3-(5-chlor-1' h ,3 h -spiro[1-benzofuran-2,4'-piperidin]-1'-yl)-2-hydroxypropyl]oxy}-4-hydroxybenzoyl)pyrrolidin-3-ol, 3(r)-1-(2-{[(2s)-3-(5-chlor-1' h ,3 h -spiro[1-benzofuran-2,4'-piperidin]-1'-yl)-2-hydroxypropyl]oxy}-4-hydroxybenzoyl)pyrrolidin-3-ol, 3-{[(2s)-3-(5-chlor-1' h ,3 h -spiro[1-benzofuran-2,4'-piperidin]-1'-yl)-2-hydroxypropyl]oxy}-4-(morpholin-4-ylcarbonyl)phenol, und deren pharmazeutisch annehmbaren salzen und solvaten.