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in dat geval sterft het botweefsel af door verlies van bloedtoevoer naar het bot.
this is where the bone tissue dies because the blood supply has been lost (death of bone tissue caused by loss of blood supply to the bone).
hierdoor vermindert osteolyse en wordt proliferatief tumorstroma vervangen door niet-proliferatief, gedifferentieerd, dicht nieuw botweefsel.
consequently, osteolysis is reduced and proliferative tumour stroma is replaced with non-proliferative, differentiated, densely woven new bone.