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methylkviksølv i miljøet stammer hovedsagelig, om ikke udelukkende, fra methylering af uorganisk kviksølv.
environmental methylmercury arises largely, if not solely, from the methylation of inorganic mercury.
væsentlige biotransformationer hos hunde inkluderer hydroxylering, konjugering med glukoronsyre og n-methylering i leveren.
major biotransformations in the dog include hydroxylation, glucuronic acid conjugation and n- methylation in the liver.
den aktive metabolit metaboliseres yderligere i to inaktive forbindelser ved s - methylering eller konjugering med cystein.
the active metabolite is further metabolised to two inactive compounds by s- methylation or conjugation with cysteine.
ved homocystinuri nedsætter betain homocysteinindholdet i blodet ved at fremme en reaktion, der kaldes methylering, hvorved homocystein tilbagedannes til methionin.
in homocystinuria, betaine reduces homocysteine levels in the blood by facilitating a reaction in the body called ‘methylation’, which converts homocysteine back into methionine.
der findes tre typer af initial metaboliske reaktioner, direkte n-glukuronidering, direkte n-methylering og cytochrom p450 katalyseret oxidation.
there are three types of initial metabolic reactions; direct n-glucuronidation, direct n-methylation and cytochrome p450 catalysed oxidation.
levodopa metaboliseres i høj grad til forskellige metabolitter, hvor decarboxylering via dopadecarboxylase (ddc) og o- methylering via cathecol- o- methyltransferase (comt) er de vigtigste metaboliseringsveje.
levodopa is extensively metabolised to various metabolites, decarboxylation by dopa decarboxylase (ddc) and o-methylation by catechol-o-methyltransferase (comt) being the most important pathways.