Вы искали: receptorjih (Словенский - Английский)

telmisartan nima delnega agonističnega učinka na receptorjih at1.
telmisartan does not exhibit any partial agonist activity at the at1 receptor.

v predkliničnih študijah enzalutamid ni deloval agonistično na androgenskih receptorjih.
in preclinical studies enzalutamide lacks androgen receptor agonist activity.

glavni presnovki so imeli najmanj trinajstkrat manjšo aktivnost na melatoninskih receptorjih kot tasimelteon.
major metabolites had 13-fold or less activity at melatonin receptors compared to tasimelteon.

nalmefen je modulator opioidnega sistema z značilnimi profilom delovanja na receptorjih μ, δ in κ.
nalmefene is an opioid system modulator with a distinct μ, δ, and κ receptor profile.

sarolaner ima večjo afiniteto za funkcionalno blokado receptorjev pri insektih in pršicah kot pri receptorjih sesalcev.
sarolaner exhibits higher functional potency to block insect/acarine receptors compared to mammalian receptors.

v raziskavi sočutne uporabe pri 64 bolnikih so bili za 46 bolnikov na voljo podatki o potrjenih receptorjih ldl.
atorvastatin should be used as an adjunct to other lipid-lowering treatments (e. g.

aklidinij je kompetitivni, selektivni antagonist muskarinskih receptorjev z daljšim časom zadrževanja na receptorjih m3 kot receptorjih m2.
aclidinium is a competitive, selective muscarinic receptor antagonist, with a longer residence time at the m3 receptors than the m2 receptors.

aprepitant je selektivni antagonist z veliko afiniteto na humanih receptorjih za substanco p nevrokinin 1 (nk1).
aprepitant is a selective high-affinity antagonist at human substance p neurokinin 1 (nk1) receptors.

po podaljšani uporabi drugih učinkovin z aktivnostjo na µ-opioidnih receptorjih so po nenadni prekinitvi zdravljenja opazili odtegnitvene simptome.
after prolonged use of other substances with µ-opioid receptor activity, symptoms of withdrawal were observed after abrupt interruption of the treatment.

primarna pot presnove vilanterola je o-dealkilacija v številne presnovke z bistveno manjšo agonistično aktivnostjo na adrenergičnih receptorjih beta1 in beta2.
the primary metabolic routes for vilanterol are o-dealkylation to a range of metabolites with significantly reduced beta1- and beta2-adrenergic agonist activity.

predklinične raziskave kažejo, da gvanfacin modulira pošiljanje signalov v prefrontalnem korteksu in bazalnih ganglijih z neposrednim modificiranjem sinaptičnega noradrenalinskega prenosa na adrenergičnih receptorjih alfa2a.
preclinical research suggests guanfacine modulates signalling in the prefrontal cortex and basal ganglia through direct modification of synaptic noradrenalin transmission at the alpha 2- adrenergic receptors.

učinkovanje buprenorfina se pripisuje njegovim počasi reverzibilnim lastnostim na -opioidnih receptorjih, ki lahko prek daljšega obdobja zmanjša potrebo odvisnosti bolnikov od drog.
its activity in opioid maintenance treatment is attributed to its slowly reversible properties with the -opioid receptors which, over a prolonged period, might minimise the need of addicted patients for drugs.

aklidinijev bromid je kompetitiven, selektivni antagonist muskarinskih receptorjev (znan tudi kot antiholinergik) z daljšim časom zadrževanja na receptorjih m3 kot receptorjih m2.
aclidinium bromide is a competitive, selective muscarinic receptor antagonist (also known as an anticholinergic), with a longer residence time at the m3 receptors than the m2 receptors.

pri pljučni arterijski hipertenziji in srčnem popuščanju, če ni antagonizma na endotelinskih receptorjih, so povišane koncentracije et-1 močno povezane z resnostjo in prognozo teh bolezni.
in pulmonary arterial hypertension and heart failure, in the absence of endothelin receptor antagonism, elevated et- 1 concentrations are strongly correlated with the severity and prognosis of these diseases.

učinkovitost aripiprazola pri shizofreniji in bipolarni i motnji je domnevno posledica kombinacije delnega agonizma na dopaminskih receptorjih d2 in serotoninskih receptorjih 5- ht1a ter antagonizma na serotoninskih receptorjih 5- ht2a.
19 it has been proposed that aripiprazole’ s efficacy in schizophrenia and bipolar i disorder is mediated through a combination of partial agonism at dopamine d2 and serotonin 5ht1a receptors and antagonism of serotonin 5ht2a receptors.

ti encimi se nahajajo na nekaterih receptorjih na površini rakavih celic, kjer sodelujejo pri rasti in širjenju rakavih celic, ter v krvnih žilah, ki oskrbujejo tumor, kjer sodelujejo pri nastanku novih krvnih žil.
these enzymes can be found in some receptors on the surface of cancer cells, where they are involved in the growth and spread of cancer cells, and in the blood vessels that supply the tumours, where they are involved in the development of new blood vessels.

valsartan nima delnega agonističnega učinka na receptorjih at1, njegova afiniteta za receptorje at1 pa je veliko (približno 20.000-krat) večja kot za receptorje at2.
valsartan does not exhibit any partial agonist activity at the at1 receptor and has much (about 20,000-fold) greater affinity for the at1 receptor than for the at2 receptor.

"kritične vrednosti" pomeni koncentracije onesnaževal v atmosferi, nad katerimi se v skladu s sedanjim nivojem znanja na receptorjih, kot so ljudje, rastline, ekosistemi ali material, lahko pojavijo neposredni škodljivi vplivi;
'critical levels` means the concentration of pollutants in the atmosphere above which direct adverse effects on receptors, such as human beings, plants, ecosystems or materials, may occur, according to present knowledge;