Şunu aradınız:: asaglünafareliini (Estonca - İngilizce)

asaglünafareliini
azagly-nafarelin

asaglünafareliini 18,5 mg
azagly-nafarelin 18.5 mg

gonazon sisaldab toimeainena asaglünafareliini.
gonazon contains the active substance azagly-nafarelin.

asaglünafareliini toime pikaajalisel kasutamisel sugukaladel ei ole uuritud
the long term effects of azagly-nafarelin on treated broodstock fish have not been studied.

asaglünafareliini jaotumist ja metabolismi lõhilaste organismis ei ole uuritud.
the distribution and metabolism of azagly-nafarelin have not been studied in the target species.

gonazon sisaldab asaglünafareliini, mis on kehaomase hormooni gonadoliberiini (gnrh) analoog.
gonazon contains azagly-nafarelin, which is an analogue of a natural hormone called gonadotrophin- releasing hormone (gnrh).

asaglünafareliini kliirens pärast sama annuse intravenoosset manustamist on 0, 46 l/ h ja eliminatsiooni poolväärtusaeg 1, 8 tundi.
the clearance of azagly-nafarelin following intravenous administration of the same dose is 0.46 l/ h and the elimination half-life is 1.8 hours.

asaglünafareliini jaotusruumala pärast intravenoosse boolusannuse manustamist (võrdeliselt ühes implantaadis sisalduvale annusele) on 0, 12 l/ kg.
the apparent volume of distribution of azagly-nafarelin following intravenous bolus administration, at a dose equivalent to the content of one implant, is 0.12 l/ kg.

metabolism ja eritumine: asaglünafareliini kliirens pärast sama annuse intravenoosset manustamist on 0,46 l/h ja eliminatsiooni poolväärtusaeg 1,8 tundi.
metabolism and excretion: the clearance of azagly-nafarelin following intravenous administration of the same dose is 0.46 l/h and the elimination half-life is 1.8 hours.

jaotumine: asaglünafareliini jaotusruumala pärast intravenoosse boolusannuse manustamist (võrdeliselt ühes implantaadis sisalduvale annusele) on 0,12 l/kg.
distribution: the apparent volume of distribution of azagly-nafarelin following intravenous bolus administration, at a dose equivalent to the content of one implant, is 0.12 l/kg.

asaglünafareliini poolestusaeg (t½) ja toimeaeg pärast intraperitoneaalset manustamist vikerforellile doosis 32 μg/kg kehamassi kohta on vastavalt 4,9 ja 6,8 tundi.
the elimination half-life (t1/2) and mean residence time of azagly-nafarelin in trout after ip treatment of 32 µg/kg bw are 4.9 h and 6.8 h, respectively.

Ühe implantaadi subkutaanse manustamise järel koerale (keskmine kaal 10 kg) saavutatakse asaglünafareliini maksimaalne kontsentratsioon seerumis (0, 13 µg/ ml) umbes 3, 5 tunni pärast.
following subcutaneous administration of a single implant to dogs (approximate weight of 10 kg), maximum serum concentrations (0.13 µg/ ml) of azagly-nafarelin are reached around 3.5 hours.