Şunu aradınız:: metafażi (Maltaca - İngilizce)

in-numru ta’ metafażi analizzati kull annimal;
number of metaphases analyzed per animal;

mill-anqas 100 metafażi imxerrda sewwa ghal kull kultura huma analizzati għal aberrazzjonijiet kromożomali.
at least 100 well-spread metaphases per culture are analyzed for chromosomal aberrations.

il-preparazzjonijiet huma msoffija u ċ-ċelloli tal-metafażi huma analizzati għall-annormalitajiet.
preparations are stained and metaphase cells are analyzed for chromosomal abnormalities.

identità tas-sustanza li twaqqaf il-metafażi, il-konċentrazzjoni tagħha u kemm idum it-trattament,
identity of metaphase arresting substance, its concentration and duration of treatment,

għandhom jiġu analizzati għall-inqas 100 metafażi mferxin sew għal kull annimal (jiġifieri minimu ta' 500 metafażi kull grupp).
for each animal at least 100 well-spread metaphase should be analysed (i.e. a minimum of 500 metaphases per group).

f’linji ta’ ċelloli stabbiliti l-metafażi biss li jkun fih ± 2 ċentromeri tan-numru modali huma analizzati.
in established cell lines only metaphases containing ± 2 centromeres of the modal number are analyzed.

analiżi fish (>/= 200 ċelloli) tista' tintuża għal evalwazzjonijiet ċitoġenetiċi wara l-linja bażi jekk ma jkunx hemm>/= 20 metafażi disponibbli.
fish analysis (>/= 200 cells) could be used for post-baseline cytogenetic assessments if >/= 20 metaphases were not available.

qabel ma jiġu sakrifikati, l-annimali huma ttrattati b'aġent li jwaqqaf l-metafażi (eż. kolċiċina jew colcemid®).
prior to sacrifice, animals are treated with a metaphase arresting agent (e.g. colchicine or colcemid®).

carbaglu ma wera l-ebda attività mutaġenika sinifikanti f’sensiela ta’ testijiet dwar il-genotossiċità mwettqa in vitro (ames test, analiżi tal-metafażi tal-limfoċiti fil-bniedem) u in vivo (eżami mikronuklejari fil-far).
carbaglu showed no significant mutagenic activity in a battery of genotoxicity tests performed in vitro (ames test, human lymphocyte metaphase analysis) and in vivo (micronucleus test in rat).