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英语

hypophysitis (hypopituitarism)

丹麦语

hypofysitis (hypopituitarisme)

最后更新: 2017-04-26
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英语

Grade 4 hypophysitis

丹麦语

Grad 4 hypofysitis

最后更新: 2017-04-26
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英语

hypopituitarism (including hypophysitis)c, hypothyroidismc

丹麦语

hypopituitarisme (herunder hypofysitis)c, hypotyroidismec

最后更新: 2017-04-26
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英语

Hypophysitis resolved in 7 patients, 2 with sequelae.

丹麦语

Hypofysitis gik over hos 7 patienter, 2 med sequelae.

最后更新: 2017-04-26
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英语

Symptomatic Grade 2 or 3 hypothyroidism, hyperthyroidism, hypophysitis,

丹麦语

Symptomatisk grad 2 eller 3 hypotyroidisme, hypertyroidisme, hypofysitis

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英语

adrenal insufficiency, hypopituitarism, hypophysitis, thyroiditis, diabetic ketoacidosis

丹麦语

binyrebarkinsufficiens, hypopituitarisme, hypofysitis, tyroiditis, diabetisk ketoacidose

最后更新: 2017-04-26
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英语

adrenal insufficiency, hypopituitarism, hypophysitis, hyperthyroidism, thyroiditis, hyperglycaemiab

丹麦语

binyrebarkinsufficiens, hypopituitarisme, hypofysitis, hypertyroidisme, tyroiditis, hyperglykæmib

最后更新: 2017-04-26
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英语

Hypophysitis led to discontinuation of pembrolizumab in 4 (0.1%) patients.

丹麦语

Hypofysitis medførte seponering af pembrolizumab hos 4 (0,1%) patienter.

最后更新: 2017-04-26
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英语

There were no reports of hypophysitis, diabetes mellitus, or diabetic ketoacidosis in these studies.

丹麦语

Der var ingen rapporter om hypofysitis, diabetes mellitus eller diabetisk ketoacidose i disse studier.

最后更新: 2017-04-26
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英语

For symptomatic hypophysitis, nivolumab should be withheld, and hormone replacement should be initiated as needed.

丹麦语

Ved symptomatisk hypofysitis bør nivolumabdosering udsættes og hormonsubstitution initieres efter behov.

最后更新: 2017-04-26
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英语

Symptomatic endocrinopathies (including hypothyroidism, hyperthyroidism, hypophysitis, adrenal insufficiency and diabetes)

丹麦语

Symptomatiske endokrinopatier (inklusive hypotyroidisme, hypertyroidisme, hypofysitis, binyrebarkinsufficiens og diabetes)

最后更新: 2017-04-26
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英语

The median time to onset of hypophysitis was 3.7 months (range 1 day to 11.9 months).

丹麦语

Den mediane tid til indtræden af hypofysitis var 3,7 måneder (interval: 1 dag til 11,9 måneder).

最后更新: 2017-04-26
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英语

For symptomatic Grade 2 or 3 hypophysitis, nivolumab or nivolumab in combination with ipilimumab should be withheld, and hormone replacement should be initiated as needed.

丹麦语

Ved symptomatisk grad 2 eller 3 hypofysitis bør nivolumab eller nivolumab i kombination med ipilimumab udsættes og hormonsubstitution initieres efter behov.

最后更新: 2017-04-26
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英语

Severe adverse reactions in the endocrine glands, such as hypophysitis and thyroiditis that are not adequately controlled with hormone replacement therapy or high-dose immunosuppressive therapy

丹麦语

Alvorlige bivirkninger i de endokrine kirtler, som f.eks. hypophysitis og tyroiditis, som ikke er tilstrækkeligt kontrolleret med hormonsubstitutionsbehandling eller højdosis immunosuppressiv behandling

最后更新: 2017-04-26
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英语

Nivolumab or nivolumab in combination with ipilimumab must be permanently discontinued for life-threatening (Grade 4) hypophysitis.

丹麦语

Nivolumab eller nivolumab i kombination med ipilimumab skal seponeres permanent i tilfælde af livstruende (grad 4) hypofysitis.

最后更新: 2017-04-26
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英语

Severe endocrinopathies, including hypophysitis, type 1 diabetes mellitus, diabetic ketoacidosis, hypothyroidism, and hyperthyroidism have been observed with pembrolizumab treatment.

丹麦语

Svære endokrinopatier, herunder hypofysitis, type 1-diabetes mellitus, diabetisk ketoacidose, hypotyroidisme og hypertyroidisme er observeret i forbindelse med pembrolizumab-behandling.

最后更新: 2017-04-26
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英语

Patients should be monitored for signs and symptoms of hypophysitis (including hypopituitarism and secondary adrenal insufficiency) and other causes excluded.

丹麦语

Patienterne skal monitoreres for tegn og symptomer på hypofysitis (inklusive hypofyseinsufficiens (hypopituitarisme) og sekundær binyrebarkinsufficiens), og andre årsager skal udelukkes.

最后更新: 2017-04-26
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英语

Severe endocrinopathies, including hypothyroidism, hyperthyroidism, adrenal insufficiency, hypophysitis, diabetes mellitus, and diabetic ketoacidosis have been observed with nivolumab treatment.

丹麦语

Svære endokrinopatier, herunder hypotyroidisme, hypertyroidisme, binyrebarkinsufficiens, hypofysitis, diabetes mellitus og diabetisk ketoacidose er observeret med nivolumab-behandling.

最后更新: 2017-04-26
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英语

Severe endocrinopathies, including hypophysitis (including hypopituitarism and secondary adrenal insufficiency), type 1 diabetes mellitus, diabetic ketoacidosis, hypothyroidism, hyperthyroidism and thyroiditis

丹麦语

Svære endokrinopatier, inklusive hypofysitis (inklusive hypopituitarisme og sekundær binyrebarkinsufficiens), type 1-diabetes mellitus, diabetisk ketoacidose, hypotyroidisme, hypertyroidisme og tyroiditis

最后更新: 2017-04-26
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英语

Hypophysitis occurred in 17 (0.6%) patients, including Grade 2, 3 or 4 cases in 6 (0.2%), 8 (0.3%) and 1 (<0.1%) patients, respectively, receiving pembrolizumab.

丹麦语

Hypofysitis forekom hos 17 (0,6%) patienter, som fik pembrolizumab, inklusive tilfælde af grad 2, 3 eller 4 hos henholdsvis 6 (0,2%), 8 (0,3%) og 1 (< 0,1%) patienter.

最后更新: 2017-04-26
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