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俄语

blood serum

英语

blood serum

最后更新: 2017-01-03
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俄语

6453 blood serum Сыворотка крови

英语

6453 blood serum

最后更新: 2016-12-04
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俄语

i wish senpai made the serum already.

英语

i wish senpai made the serum already.

最后更新: 2018-02-21
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俄语

immunoglobulins in the serum and at mucosal surfaces.

英语

plague may be transmitted by a flea

最后更新: 2018-02-21
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俄语

4. the collection of human serum samples in endemic areas.

英语

4. the collection of human serum samples in endemic areas.

最后更新: 2018-02-21
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俄语

the dried blood serum, prepared for the ir-spectral analysis, was investigated.

英语

the dried blood serum, prepared for the ir-spectral analysis, was investigated.

最后更新: 2018-02-21
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俄语

read more >>> http://www.supplements4news.com/extensive-ageless-serum/

英语

read more>>> http://www.supplementsecure.com/amabella-allure/

最后更新: 2018-02-21
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俄语

apply 2 or 3 doses to face and neck morning and/or evening after rha™ serum.

英语

apply 2 or 3 doses to face and neck morning and/or evening after rha™ serum.

最后更新: 2018-02-21
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俄语

read more>>> http://www.supplementscommunity.com/simple-anti-aging-serum/

英语

http://www.cheap-mlb-jerseys.us.com http://www.bostoncelticsjerseys.com

最后更新: 2018-02-21
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俄语

Сыворотка terracotta sun serum окончательно возвращается на радость всем, кто хочет активировать, усилить и продлить свой загар летом или круглый год.

英语

terracotta sun serum is ideal for all women who want to activate, intensify and prolong their tan in summer or all year round.

最后更新: 2018-02-21
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俄语

Ключевые слова: infrared spectral analysis, blood serum, infectious diseases, syndrome of angina, metabolism disturbance.

英语

keywords: infrared spectral analysis, blood serum, infectious diseases, syndrome of angina, metabolism disturbance.

最后更新: 2018-02-21
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俄语

Среди его клиентов были Мадонна и принцесса Диана. Он создал известную линию продукции, названную "serum solutions".

英语

amongst his clients were madonna and princess diana. he created a famous line of products called "serum solutions". . .

最后更新: 2018-02-21
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俄语

i bet grisha's basement is filled with these as well as the serum to make people titans. i'm calling it right now.

英语

i bet grisha's basement is filled with these as well as the serum to make people titans. i'm calling it right now.

最后更新: 2018-02-21
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俄语

Наносите утром и/вечером с помощью ватного диска или без него, перед сывороткой super aqua-serum или перед другими средствами косметического ухода.

英语

apply morning and / or evening with or without a cotton pad before super aqua-serum.

最后更新: 2018-02-21
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俄语

* 1 Надкласс: basic domains (basic-helix-loop-helix)** 1.1 Класс: Лейциновая молния (bzip)*** 1.1.1 Семейство: ap-1(-like) components; includes (c-fos/c-jun)*** 1.1.2 Семейство: creb*** 1.1.3 Семейство: c/ebp-like factors*** 1.1.4 Семейство: bzip / par*** 1.1.5 Семейство: plant g-box binding factors*** 1.1.6 Семейство: zip only** 1.2 Класс: Спираль-петля-спираль (bhlh)*** 1.2.1 Семейство: ubiquitous (Класс a) factors*** 1.2.2 Семейство: myogenic transcription factors (myod)*** 1.2.3 Семейство: achaete-scute*** 1.2.4 Семейство: tal/twist/atonal/hen** 1.3 Класс: Спираль-петля-спираль / лейциновая молния factors (bhlh-zip)*** 1.3.1 Семейство: ubiquitous bhlh-zip factors; includes usf (usf1, usf2); srebp (srebp)*** 1.3.2 Семейство: cell-cycle controlling factors; includes c-myc** 1.4 Класс: nf-1*** 1.4.1 Семейство: nf-1 (nfic)** 1.5 Класс: rf-x*** 1.5.1 Семейство: rf-x (, , )** 1.6 Класс: bhsh* 2 Надкласс: zinc-coordinating dna-binding domains** 2.1 Класс: cys4 zinc finger of nuclear receptor type*** 2.1.1 Семейство: steroid hormone receptors*** 2.1.2 Семейство: thyroid hormone receptor-like factors** 2.2 Класс: diverse cys4 zinc fingers*** 2.2.1 Семейство: gata-factors** 2.3 Класс: cys2his2 zinc finger domain*** 2.3.1 Семейство: ubiquitous factors, includes tfiiia, sp1*** 2.3.2 Семейство: developmental / cell cycle regulators; includes krüppel*** 2.3.4 Семейство: large factors with nf-6b-like binding properties** 2.4 Класс: cys6 cysteine-zinc cluster** 2.5 Класс: zinc fingers of alternating composition* 3 Надкласс: Спираль-поворот-спираль** 3.1 Класс: Гомеодомен*** 3.1.1 Семейство: homeo domain only; includes ubx*** 3.1.2 Семейство: pou domain factors; includes oct*** 3.1.3 Семейство: homeo domain with lim region*** 3.1.4 Семейство: homeo domain plus zinc finger motifs** 3.2 Класс: paired box*** 3.2.1 Семейство: paired plus homeo domain*** 3.2.2 Семейство: paired domain only** 3.3 Класс: fork head / winged helix*** 3.3.1 Семейство: developmental regulators; includes forkhead*** 3.3.2 Семейство: tissue-specific regulators*** 3.3.3 Семейство: cell-cycle controlling factors*** 3.3.0 Семейство: other regulators** 3.4 Класс: heat shock factors*** 3.4.1 Семейство: hsf** 3.5 Класс: tryptophan clusters*** 3.5.1 Семейство: myb*** 3.5.2 Семейство: ets-type*** 3.5.3 Семейство: interferon regulatory factors** 3.6 Класс: tea (transcriptional enhancer factor) domain*** 3.6.1 Семейство: tea (tead1, tead2, tead3, tead4)* 4 Надкласс: beta-scaffold factors with minor groove contacts** 4.1 Класс: rhr (rel homology region)*** 4.1.1 Семейство: rel/ankyrin; nf-kappab*** 4.1.2 Семейство: ankyrin only*** 4.1.3 Семейство: nf-at (nuclear factor of activated t-cells) (nfatc1, nfatc2, nfatc3)** 4.2 Класс: stat*** 4.2.1 Семейство: stat** 4.3 Класс: p53*** 4.3.1 Семейство: p53** 4.4 Класс: mads box*** 4.4.1 Семейство: regulators of differentiation; includes (mef2)**** 4.4.2 Семейство: responders to external signals, srf (serum response factor) ()** 4.5 Класс: beta-barrel alpha-helix transcription factors** 4.6 Класс: tata binding proteins*** 4.6.1 Семейство: tbp*** 4.7.1 Семейство: sox genes, sry*** 4.7.2 Семейство: tcf-1 (tcf1)*** 4.7.3 Семейство: hmg2-related, ssrp1*** 4.7.5 Семейство: mata** 4.8 Класс: heteromeric ccaat factors*** 4.8.1 Семейство: heteromeric ccaat factors** 4.9 Класс: grainyhead*** 4.9.1 Семейство: grainyhead** 4.10 Класс: cold-shock domain factors*** 4.10.1 Семейство: csd** 4.11 Класс: runt*** 4.11.1 Семейство: runt* 0 Надкласс: Другие факторы транскрипции** 0.1 Класс: copper fist proteins** 0.2 Класс: hmgi(y) (hmga1)*** 0.2.1 Семейство: hmgi(y)** 0.3 Класс: pocket domain** 0.4 Класс: e1a-like factors** 0.5 Класс: ap2/erebp-related factors*** 0.5.1 Семейство: ap2*** 0.5.2 Семейство: erebp*** 0.5.3 Надсемейство: ap2/b3**** 0.5.3.1 Семейство: arf**** 0.5.3.2 Семейство: abi**** 0.5.3.3 Семейство: ravcrispr систему можно адаптировать так, чтобы она действовала как транскрипционный фактор (crisprtf).

英语

conditionally active – requires activation** ii.a developmental (cell specific) – expression is tightly controlled, but, once expressed, require no additional activation – gata, hnf, pit-1, myod, myf5, hox, winged helix** ii.b signal-dependent – requires external signal for activation*** ii.b.1 extracellular ligand (endocrine or paracrine)-dependent – nuclear receptors*** ii.b.2 intracellular ligand (autocrine)-dependent - activated by small intracellular molecules – srebp, p53, orphan nuclear receptors*** ii.b.3 cell membrane receptor-dependent – second messenger signaling cascades resulting in the phosphorylation of the transcription factor**** ii.b.3.a resident nuclear factors – reside in the nucleus regardless of activation state – creb, ap-1, mef2**** ii.b.3.b latent cytoplasmic factors – inactive form reside in the cytoplasm, but, when activated, are translocated into the nucleus – stat, r-smad, nf-κb, notch, tubby, nfat=== structural ===transcription factors are often classified based on the sequence similarity and hence the tertiary structure of their dna-binding domains:*1 superclass: basic domains**1.1 class: leucine zipper factors (bzip)***1.1.1 family: ap-1(-like) components; includes (c-fos/c-jun)***1.1.2 family: creb***1.1.3 family: c/ebp-like factors***1.1.4 family: bzip / par***1.1.5 family: plant g-box binding factors***1.1.6 family: zip only**1.2 class: helix-loop-helix factors (bhlh)***1.2.1 family: ubiquitous (class a) factors***1.2.2 family: myogenic transcription factors (myod)***1.2.3 family: achaete-scute***1.2.4 family: tal/twist/atonal/hen**1.3 class: helix-loop-helix / leucine zipper factors (bhlh-zip)***1.3.1 family: ubiquitous bhlh-zip factors; includes usf (usf1, usf2); srebp (srebp)***1.3.2 family: cell-cycle controlling factors; includes c-myc**1.4 class: nf-1***1.4.1 family: nf-1 (a, b, c, x)**1.5 class: rf-x***1.5.1 family: rf-x (1, 2, 3, 4, 5, ank)**1.6 class: bhsh*2 superclass: zinc-coordinating dna-binding domains**2.1 class: cys4 zinc finger of nuclear receptor type***2.1.1 family: steroid hormone receptors***2.1.2 family: thyroid hormone receptor-like factors**2.2 class: diverse cys4 zinc fingers***2.2.1 family: gata-factors**2.3 class: cys2his2 zinc finger domain***2.3.1 family: ubiquitous factors, includes tfiiia, sp1***2.3.2 family: developmental / cell cycle regulators; includes krüppel***2.3.4 family: large factors with nf-6b-like binding properties**2.4 class: cys6 cysteine-zinc cluster**2.5 class: zinc fingers of alternating composition*3 superclass: helix-turn-helix**3.1 class: homeo domain***3.1.1 family: homeo domain only; includes ubx***3.1.2 family: pou domain factors; includes oct***3.1.3 family: homeo domain with lim region***3.1.4 family: homeo domain plus zinc finger motifs**3.2 class: paired box***3.2.1 family: paired plus homeo domain***3.2.2 family: paired domain only**3.3 class: fork head / winged helix***3.3.1 family: developmental regulators; includes forkhead***3.3.2 family: tissue-specific regulators***3.3.3 family: cell-cycle controlling factors***3.3.0 family: other regulators**3.4 class: heat shock factors***3.4.1 family: hsf**3.5 class: tryptophan clusters***3.5.1 family: myb***3.5.2 family: ets-type***3.5.3 family: interferon regulatory factors**3.6 class: tea ( transcriptional enhancer factor) domain***3.6.1 family: tea (tead1, tead2, tead3, tead4)*4 superclass: beta-scaffold factors with minor groove contacts**4.1 class: rhr (rel homology region)***4.1.1 family: rel/ankyrin; nf-kappab***4.1.2 family: ankyrin only***4.1.3 family: nfat (nuclear factor of activated t-cells) (nfatc1, nfatc2, nfatc3)**4.2 class: stat***4.2.1 family: stat**4.3 class: p53***4.3.1 family: p53**4.4 class: mads box***4.4.1 family: regulators of differentiation; includes (mef2)***4.4.2 family: responders to external signals, srf (serum response factor) ()***4.4.3 family: metabolic regulators (arg80)**4.5 class: beta-barrel alpha-helix transcription factors**4.6 class: tata binding proteins***4.6.1 family: tbp**4.7 class: hmg-box***4.7.1 family: sox genes, sry***4.7.2 family: tcf-1 (tcf1)***4.7.3 family: hmg2-related, ssrp1***4.7.4 family: ubf***4.7.5 family: mata**4.8 class: heteromeric ccaat factors***4.8.1 family: heteromeric ccaat factors**4.9 class: grainyhead***4.9.1 family: grainyhead**4.10 class: cold-shock domain factors***4.10.1 family: csd**4.11 class: runt***4.11.1 family: runt*0 superclass: other transcription factors**0.1 class: copper fist proteins**0.2 class: hmgi(y) (hmga1)***0.2.1 family: hmgi(y)**0.3 class: pocket domain**0.4 class: e1a-like factors**0.5 class: ap2/erebp-related factors***0.5.1 family: ap2***0.5.2 family: erebp***0.5.3 superfamily: ap2/b3****0.5.3.1 family: arf****0.5.3.2 family: abi****0.5.3.3 family: rav== see also ==* cdx protein family* dna-binding protein* inhibitor of dna-binding protein* nuclear receptor, a class of ligand activated transcription factors* phylogenetic footprinting* transfac database== references ====external links==* calculating transcription factor binding maps for chromatin* probability of transcription factor binding to dna* uri alon (2007).

最后更新: 2016-03-03
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