您搜索了: dezetiloksibutinin (斯洛文尼亚语 - 英语)

manj kot 0,1 % odmerka se izloči kot metabolit n-dezetiloksibutinin.
also, less than 0.1% of the administered dose is excreted as the metabolite n-desethyloxybutynin.

med metaboliti sta tudi fenilcikloheksilglikolna kislina, ki je farmakološko neaktivna, in n-dezetiloksibutinin, ki je farmakološko aktiven.
metabolites include phenylcyclohexylglycolic acid, which is pharmacologically inactive, and n-desethyloxybutynin, which is pharmacologically active.

aktivni presnovek n-dezetiloksibutinin farmakološko deluje na detruzorsko mišico pri človeku podobno kot oksibutinin v študijah in vitro, vendar ima večjo afiniteto za vezavo na parotidno tkivo kot oksibutinin.
the active metabolite, n-desethyloxybutynin, has pharmacological activity on the human detrusor muscle that is similar to that of oxybutynin in vitro studies, but has a greater binding affinity for parotid tissue than oxybutynin.

aktiven metabolit, n-dezetiloksibutinin, farmakološko vpliva na mišico detruzorja pri človeku, kar je podobno kot učinek oksibutinina pri študijah in vitro, vendar pa je njegova afiniteta za obušesno tkivo večja kot pri oksibutininu.
the active metabolite, n-desethyloxybutynin, has pharmacological activity on the human detrusor muscle that is similar to that of oxybutynin in vitro studies, but has a greater binding affinity for parotid tissue than oxybutynin.