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the researchers found that excessive secretion of agmatine, an endogenous neuromodulator present in the brain and spinal cord, may cause schizophrenia.
Οι ερευνητές ανακάλυψαν ότι η υπερβολική έκκριση αγματίνης, ενδογενή νευρορυθμιστή που υπάρχει στον εγκέφαλο και στο νωτιαίο μυελό, ενδέχεται να προκαλεί σχιζοφρένια.
最后更新： 2016-01-20
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the neuromodulator dopamine (da) plays a critical role in cognitive function across species and strategies that augment or refine da activity in the brain have been shown to improve cognitive function (nieoullon 2002). the enzyme catechol-o-methyltransferase (comt) is a key component of the da metabolic pathway (axelrod and tomchick 1958) and inhibition of the enzyme has been proposed as a cognitive enhancement strategy (apud and weinberger 2007). comt is located through- out the body with the highest expression in the liver and brain (tenhunen et al. 1994). there is a soluble (s- comt) and a membrane-bound (mb-comt) form of the enzyme. s-comt has a higher vmax but lower affin- ity for da compared with
αντενδείκνυται λόγω πιθανής επιδείνωσης άλλων συμπτωμάτων (hsu et al. 2018).
最后更新： 2020-12-04
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