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combinatorial chemistry for drug discovery.
寻找新药物的组合化学。

box 5. india's open source drug discovery initiative
方框5. 印度的 "开放源药物发明举措 "

an example of this can be india's open source drug discovery initiative (see box 5).
这方面的一个实例可以是印度的 "开放源药物发明举措 "(见方框5)。

but to take baby steps to get there, first of all we want to look at drug design and production, or drug discovery and manufacturing.
但是，要一步步的达到那里， 首先，我们在看药物的设计和产品， 或药物的发现和制造。

drug development is the process of bringing a new infectious disease vaccine or therapeutic drug to the market once a lead compound has been identified through the process of drug discovery.
药物开发是通过药物发现确定了先导化合物后，向市场推出新的传染病疫苗或治疗药物的过程。

a formal proposal has been developed, with a major focus on antimalarial drug discovery and development, and is now being considered by key private and public organizations.
有关方面已提出一项正式提议，主要着重于抗疟疾药品的发现和研制，一些重要的私人和政府组织现在正在对此进行研究。

in particular, work is ongoing to improve metagenomic screening and libraries, to reduce genetic erosion and shorten lead times in drug discovery and to scale up natural product purification from analytical to pilot level.
目前尤其是努力改进环境基因组的筛选和资料库，减少遗传侵蚀和缩短发明药品的准备期间，并把自然产品的净化工作从分析阶段提升到试验阶段。

new chemical entities (nces, also known as new molecular entities or nmes) are compounds that emerge from the process of drug discovery to specify a vaccine or antiviral candidate.
新化学实体（nce，也称新分子实体或 nme）是在药物发现过程中生成的化合物，用于确定疫苗或抗病毒候选物。

india's council of scientific and industrial research (csir) has recently launched the open source drug discovery (osdd) initiative.
印度的科学和工业研究理事会(csir)最近推出了 "开放源药物发明(osdd)举措 "。

38. systems biology, therefore, contributes to drug discovery, design and delivery, especially through rational drug design, by assisting the modelling of effects of molecules interacting with the system.
38. 因此，系统生物学有助于对分子与系统相互作用所产生的影响进行模拟，从而促进药物的发现、设计和释放，特别是通过合理的药物设计。

104. assessing the actual or potential total economic value of marine genetic resources beyond areas of national jurisdiction remains difficult owing to limited information on the exact location of the samples used, for example, in drug discovery or the development of enzymes used for industrial purposes.
104. 因为发明药物或研制工业用酶所用各种样品的确实地点的相关资料有限，仍然难以评估国家管辖范围以外区域的海洋遗传资源实际或潜在的总共经济价值。

without developments in microbial cultivation, seriological surveys, extraction and purification techniques, abilities to amplify genetic material, genomics techniques, and drug discovery, design and delivery, current bioprospecting efforts would not be possible.
如果没有在微生物培养、血清学观测、提纯技术、遗传物质扩增能力、基因组技术及药物的发现、设计和释放等方面取得了进展，是不可能发展出目前的生物勘探的。

they argue therefore that the oss development model could be applied in biology and that such a new approach - the open source drug discovery - could significantly reduce the cost of discovering, developing and manufacturing cures for tropical diseases, an area where research is badly underfunded.
因此他们认为，生物学领域可以采用开放源码软件发展模式，而且以开放源码开发药物这种新方法可以极大地降低治疗热带疾病这一研究经费严重不足领域的药物发明、开发和制造费用。

and really this is the fourth of these molecules to kind of graduate from our little pipeline of drug discovery, two of which -- a topical drug for lymphoma of the skin, an oral substance for the treatment of multiple myeloma -- will actually come to the bedside for first clinical trial in july of this year.
这真的是第四种分子 从我们小小的药物发现管道里毕业 其它两种 - 一种是常用药 用于治疗皮肤癌， 另一种是治疗几种骨髓癌的口服药 - 将很快来到床边 今年7月进入初期临床试验。