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autograft
irnexxa

incidence of autograft
inċidenza ta’ awtotrapjant

all of the patients were eligible for an autograft.
il-pazjenti kollha kienu eliġibbli għall-awtograft.

osigraft was at least as effective as bone autograft, the standard treatment.
osigraft kien mill-anqas effikaċi daqs trapjant awtoġenu tal-għadam, it-trattament standard.

in the main study, opgenra was not as effective as autograft in patients who were eligible for an autograft.
fl-istudju ewlieni, opgenra ma kienx effettiv daqs awtograft f’pazjenti li kienu eliġibbli għall-awtograft.

in addition, opgenra had advantages over autograft, including shorter operations, less blood loss and less pain.
barra minn hekk, opgenra għandu vantaġġi fuq awtograft, inklużi, operazzjonijiet iqsar, inqas telf ta’ demm u inqas uġigħ.

the main study of osigraft was carried out in 122 patients with unhealed tibial fractures who were treated either with the medicine or with an autograft.
l-istudju prinċipali ta’ osigraft sar f'122 pazjent bi ksur tibjali mhux imfejjaq li ġie kkurat jew bil- mediċina jew bi trapjant awtoġenu.

opgenra is indicated for posterolateral lumbar spinal fusion in adult patients with spondylolisthesis where autograft has failed or is contra-indicated.
opgenra hu indikat għal fużjoni spinali lombari posterolaterali f’pazjenti adulti li għandhom spondilolisteżi meta l-awtograft falla jew hu kontra-indikat.

after two years, treatment with opgenra was successful in 39% of the patients, compared with 49% with autograft.
wara sentejn, il-kura b’opgenra kienet ta’ suċċess f’39% tal-pazjenti, meta mqabbla ma’ 49% b’awtograft.

despite the lower effectiveness, there was sufficient evidence from the study and from the published literature to support the use of opgenra in patients in whom autograft has failed or who must not undergo the procedure.
minkejja l-effikaċja iktar baxxa, kien hemm biżżejjed evidenza mill-istudju u mil-letteratura ppubblikata li tappoġġja l-użu ta’ opgenra f’pazjenti li fuqhom, awtograft ma jkunx irnexxa jew li ma jkollhomx għalfejn jgħaddu mill-proċedura.

however, there were no differences in the incidence of these adverse events compared with patients who received bone autograft, except in the case of osteomyelitis for which the incidence of osteomyelitis was statistically higher in the autograft group.
imma, kien hemm differenzi fl- inċidenza ta ’ dawn l - episodji avversi a paragun ma 'pazjenti li ngħataw awtotrapjant, barra mill- każ ta' ostejomijeliti li għalihom l- inċidenza ta 'ostejomijeliti kienet statistikament ogħla fil- grupp ta ’ l- awtotrapjant.

histological evidence from animal studies of lumbar interbody fusion using anterior or posterior surgical approaches showed dibotermin alfa administered with titanium, peek or allograft interbody devices was biocompatible and produced consistently high rates of fusion independent of surgical approach or device material with less fibrous tissue evident compared with autograft.
evidenza istoloġika minn studji fuq il-bhejjem tal-fużjoni interkorporali lumbar bl-użu ta’ approċċ kiruġiku anterjuri jew posterjuri wera li dibotermin alfa mogħti mat-titanju, peek jew tagħmir ta’ trapjant tal-għadam interkorprali kien bijokompatibbli u produċa b’mod konsistenti rati għoljin ta’ fużjoni, indipendentement mill-approċċ kirurġiku jew materjal ta’ tagħmir b’inqas tessut fibruż evidenti meta mqabbel mat-trapjant tal-għadam.

opgenra is used only in patients who have previously had surgery using an autograft (a bone graft taken from their own body, usually the hip) that has failed or when an autograft must not be carried out.
opgenra jintuża biss f’pazjenti li diġà kellhom kirurġija permezz ta’ awtograft (graft tal-għadma meħuda minn ġisimhom stess, ġeneralment il-ġenbejn) li ma jkunx irnexxa jew meta ma jkunx jista’ jsir awtograft.

treatment of non-union of tibia of at least 9 month duration, secondary to trauma, in skeletally mature patients, in cases where previous treatment with autograft has failed or use of autograft is unfeasible.
it-trattament għal tibja li ma tagħqadx għal tal-anqas 9 xhur żmien, sekondarja għat-trawma, f’pazjenti bi skeletru matur, f’każi fejn it-trattament ta’ qabel bl-awtotrapjant ma kienx irnexxa jew l-użu tal-awtotrapjant mhux prattiku.

the study compared surgery using opgenra and surgery using bone autografts.
l-istudju qabbel kirurġija bl-użu ta’ opgenra u kirurġija bl-użu ta’ awtografts tal-għadam.