您搜索了: juxtaglomerulari (马耳他语 - 英语)

is-sejbiet tossikoloġiċi magħrufa sew minn studji li kienu saru qabel l-użu kliniku b’inibituri ta’ l- enzimi li jibdlu l-angiotensin u b’ antagonisti tar-riċetturi ta’ angiotensin ii kienu: tnaqqis fil-parametri taċ-ċelluli l-ħomor (eritroċiti, emoglobina, ematokrit), bidliet ta’ l-emodinamika renali (żieda fin- nitroġenu ta’ l-urea fid-demm u krejatinina), żieda fl-attività tar-renin fil-plażma, ipertrofija/iperplasija taċ-ċelluli juxtaglomerulari, u ħsara mukożali gastrika.
toxicological findings also well known from preclinical studies with angiotensin converting enzyme inhibitors and angiotensin ii receptor antagonists were: a reduction of red cell parameters (erythrocytes, haemoglobin, haematocrit), changes of renal haemodynamics (increased blood urea nitrogen and creatinine), increased plasma renin activity, hypertrophy/hyperplasia of the juxtaglomerular cells and gastric mucosal injury.