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der er identificeret tre hovedmetaboliske udskillelsesveje:
there are three main metabolic pathways identified:
Last Update: 2012-04-12
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der er identificeret tre hovedmetaboliske udskillelsesveje: 1) o-demetylering af en eller begge sidekæder, efterfulgt af oxidering til carboxylsyre; 2) oxidering af acetylengruppen efterfulgt af hydrolyse til arylcarboxylsyre; og 3) aromatisk hydroxylering af phenyl-acetylengruppen.
there are three main metabolic pathways identified: 1) o-demethylation of either side chain or both, followed by oxidation to the carboxylic acids; 2) oxidation of the acetylene moiety followed by hydrolysis to the aryl carboxylic acid; and 3) aromatic hydroxylation of the phenyl-acetylene moiety.
Last Update: 2017-04-26
Usage Frequency: 1
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