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der er identificeret tre hovedmetaboliske udskillelsesveje:
there are three main metabolic pathways identified:
最終更新: 2012-04-12
使用頻度: 5
品質:
der er identificeret tre hovedmetaboliske udskillelsesveje: 1) o-demetylering af en eller begge sidekæder, efterfulgt af oxidering til carboxylsyre; 2) oxidering af acetylengruppen efterfulgt af hydrolyse til arylcarboxylsyre; og 3) aromatisk hydroxylering af phenyl-acetylengruppen.
there are three main metabolic pathways identified: 1) o-demethylation of either side chain or both, followed by oxidation to the carboxylic acids; 2) oxidation of the acetylene moiety followed by hydrolysis to the aryl carboxylic acid; and 3) aromatic hydroxylation of the phenyl-acetylene moiety.
最終更新: 2017-04-26
使用頻度: 1
品質: