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5-hydroxymethylcytosine has been shown to behave like its precursor, 5-methylcytosine, in bisulfite conversion experiments.
5-hydroxymethylcytosine has been shown to behave like its precursor, 5-methylcytosine, in bisulfite conversion experiments.
Ultimo aggiornamento 2016-03-03
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therefore, bisulfite sequencing data may need to be revisited to verify whether the detected modified base is 5-methylcytosine or 5-hydroxymethylcytosine.
therefore, bisulfite sequencing data may need to be revisited to verify whether the detected modified base is 5-methylcytosine or 5-hydroxymethylcytosine.
Ultimo aggiornamento 2016-03-03
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the lab of l. aravind used bioinformatic tools to predict that the tet family of enzymes would likely oxidize 5-methylcytosine to 5-hydroxymethylcytosine.
the lab of l. aravind used bioinformatic tools to predict that the tet family of enzymes would likely oxidize 5-methylcytosine to 5-hydroxymethylcytosine.
Ultimo aggiornamento 2016-03-03
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==history==5-hydroxymethylcytosine was observed by skirmantas kriaucionis, an associate at the heintz lab, who was looking for levels of 5-methylcytosine in two different neurons.
==history==5-hydroxymethylcytosine was observed by skirmantas kriaucionis, an associate at the heintz lab, who was looking for levels of 5-methylcytosine in two different neuron types.
Ultimo aggiornamento 2016-03-03
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