Sie suchten nach: præimplantationstab (Dänisch - Englisch)

hos hunnerne blev dog set super- ovulation og let forhøjet præimplantationstab
in reproductive toxicity studies with topotecan in rats there was no effect on male or female fertility; however, in females super-ovulation and slightly increased pre-implantation loss were observed.

i reproduktionsstudier hos rotter var effekten på fertiliteten øget præimplantationstab ved orale doser på 1 mg/kg/døgn og derover.
in reproductive studies in rats by the oral route effects on fertility consisted of increased preimplantation losses at dose levels of 1 mg/kg/day and higher.

hvis eventuelle indledende undersøgelser ikke tyder på et stort potentiale for præimplantationstab, kan behandlingen udvides til at omfatte hele drægtighedsperioden fra parringen til dagen før den planlagte aflivning.
if preliminary studies, when available, do not indicate a high potential for preimplantation loss, treatment may be extended to include the entire period of gestation, from mating to the day prior to scheduled kill.

i reproduktionstoksiske forsøg af topotecan til rotter sås ingen effekt på fertiliteten hos hverken hanner eller hunner.hos hunnerne blev dog set super-ovulation og let forhøjet præimplantationstab
in reproductive toxicity studies with topotecan in rats there was no effect on male or female fertility; however, in females super-ovulation and slightly increased pre-implantation loss were observed.

i reproduktionstoksiske forsøg af topotecan til rotter sås ingen effekt på fertilitet hos hverken hanner eller hunner.hos hunnerne blev dog set super-ovulation og let forhøjet præimplantationstab.
43 in reproductive toxicity studies with topotecan in rats there was no effect on male or female fertility; however, in females super-ovulation and slightly increased pre-implantation loss were observed.

der blev observeret en påvirkning af fertiliteten hos hundyr ved et fald i implantationer og en øgning i præimplantationstab ved doser på 70 mg/kg (5 gange plasmaeksponeringen hos patienter).
an effect on female fertility was observed in the form of a decrease in implantations and an increase in pre-implantation loss at 70 mg/kg (5-fold the plasma exposure level in patients).

i det 26-ugers specifikke fertilitetsstudie med vismodegib hos rotter blev vismodegib-relaterede virkninger på hunners kønsorganer observeret ved 100 mg/kg/dag umiddelbart efter behandlingsophør, herunder fald i implantationer, øget procent af præimplantationstab og nedsat antal hunner med levedygtige fostre.
in the dedicated 26-week vismodegib rat fertility study, vismodegib-related effects on female reproductive organs were observed at 100 mg/kg/day immediately after treatment discontinuation, including decreased implantations, increased percent preimplantation loss, and decreased number of dams with viable embryos.