Sie suchten nach: morpholinoaniline (Englisch - Französisch)

nnr in dmso 1.46 (m) axial h's of the cyclohexyl 1.72 (m)–1.91 (m) 2.08 (masked) the ch2's of the cyclopentyl 2.21 (m) 8h 2.09 (m) equatorial h's of the cyclohexyl 3.02 (bs) axial h 4 3.71 (bt) axial h 1 3.98 (s) 2h phenyl-c h 2 —cn 4.84 ch of the cyclopentyl 7.36–7.97 aa′bb′ phenyl 8.06 (bs) 3h —nh 8.81 (s) 1h c h ═n 10.46 (bs) 1h nh example 82 trans-n2-(4-aminocyclohexyl)-9-cyclopentyl-n6-[4-(4-morpholinyl)-phenyl]-9h-purin-2,6-diamine dihydrochloride stage 1: 2-chloro-9-cyclopentyl-n-[4-(4-morpholinyl)phenyl]-9h-purin-6-amine 257 mg of the product obtained in stage 1 of example 1 in 4 ml of n-butanol and 214 mg of 4-morpholinoaniline are introduced at ambient temperature and the reaction medium is agitated for 24 hours at ambient temperature, followed by separating, rinsing with ether then drying under reduced pressure at 50° c. in this way 286 mg of expected product is obtained.
rmn dans dmso 1,46 (m) h axiaux du cyclohexyle 1,72 (m) -1,91 (m) 2,08 (masqué) les c h 2 du cyclopentyle 2,21 (m) 8h 2,09 (m) h équatoriaux du cyclohexyle 3,02 (sl) h 4 axial 3,71 (tl) h 1 axial 3,98 (s) 2h phényl-c h 2 -cn 4,84 ch du cyclopentyle 7,36-7,97 aa'bb' phényle 8,06 (sl) 3h -nh 8,81 (s) 1h c h =n 10,46 (sl) 1h nh exemple 82 : dichlorhydrate de trans-n2-(4-aminocyclohexyl)-9-cyclopentyl-n6-[4-(4-morpholinyl)-phényl]-9h-purin-2,6-diamine. stade 1 : 2-chloro-9-cyclopentyl-n-[4-(4-morpholinyl) phényl]-9h-purin-6-amine.