Sie suchten nach: pegaspargase (Englisch - Maltesisch)

the active substance is pegaspargase.
is-sustanza attiva hi pegaspargase.

1 ml contains 750 u of pegaspargase.
1 ml fih 750 u ta’ pegaspargase.

it contains the active substance pegaspargase.
fih is-sustanza attiva pegaspargase.

one ml of solution contains 750 units pegaspargase .
1 ml ta' soluzzjoni fih 750 unità ta' pegaspargase.

no studies of reproductive toxicity were conducted with pegaspargase.
ma sarux studji bi pegaspargase dwar tossiċità riproduttiva.

one vial of 5 ml solution contains 3750 units of pegaspargase.
kunjett wieħed ta' soluzzjoni ta' 5 ml fih 3750 unità ta' pegaspargase.

it is not known whether pegaspargase is excreted into breast milk.
mhux magħruf jekk pegaspargase jiġix eliminat mill-ħalib tas-sider tal-bniedem.

it is not known whether pegaspargase is excreted into the breast milk.
mhux magħruf jekk pegaspargase jiġix eliminat fil-ħalib tas-sider tal-bniedem.

no studies investigating the effect of pegaspargase on fertility have been performed.
ma twettqux studji li jinvestigaw l-effett ta’ pegaspargase fuq il-fertilità.

one ml of solution contains 750 units (u)** of pegaspargase*.
1 ml ta' soluzzjoni fih 750 unità (u)** ta' pegaspargase*.

specific antibodies to pegaspargase have been measured; uncommonly they were associated to hypersensitivity reactions.
antikorpi speċifiċi għal pegaspargase ġew imkejla; b’mod mhux komuni ġew assoċjati ma’ reazzjonijiet ta' sensittività eċċessiva.

pegaspargase was well tolerated both in rats and dogs when administered intravenously in single dose up to 500 u/kg.
pegaspargase ġie ttollerat tajjeb kemm fil-firien kif ukoll fil-klieb meta mogħti ġol-vina f'doża waħda sa 500 u/kg.

long-term investigations of carcinogenicity or studies of the effect on fertility in animals were not conducted with pegaspargase.
ma sarux investigazzjonijiet fit-tul dwar il-karċinoġeniċità jew studji dwar l-effett fuq il-fertilità fl- annimali b’pegaspargase.

an indirect interaction cannot be ruled out between pegaspargase and oral contraceptives due to pegaspargase hepatotoxicity that may impair the hepatic clearance of oral contraceptives.
interazzjoni indiretta ma tistax tiġi eskluża bejn pegaspargase u kontraċettivi orali minħabba l- epatotossiċità ta' pegaspargase li tista' tfixkel it-tneħħija tal-kontraċettivi orali mill-fwied.

therefore and due to its pharmacological properties, oncaspar should not be used during pregnancy unless the clinical conditions of the woman require treatment with pegaspargase.
għalhekk, u minħabba l-proprjetajiet farmakoloġiċi tiegħu, oncaspar m'għandux jintuża waqt it-tqala, ħlief jekk il-kundizzjonijiet kliniċi tal-mara jkunu jeħtieġu kura b'pegaspargase.

as pegaspargase is a protein with a high molecular weight, it is not excreted renally, and no dose adjustment is necessary in patients with renal impairment.
billi pegaspargase hu proteina b’piż molekulari għoli, ma jiġix eliminat mill-kliewi, u l-ebda aġġustament fid-doża mhu meħtieġ f’pazjenti b’indeboliment tal-kliewi.

as pegaspargase is a protein with a high molecular weight, it is not excreted renally, and no change of pharmacokinetic of oncaspar in patients with renal impairment is foreseen.
billi pegaspargase hu proteina b'piż molekulari għoli, ma jiġix eliminat mill-kliewi, u mhi mistennija l-ebda bidla fil-farmakokinetika ta' oncaspar f'pazjenti b'indeboliment tal-kliewi.

oncaspar contains pegaspargase, which is an enzyme that breaks down l-asparagine, an important building block of proteins without which cells cannot survive.
oncaspar fih pegaspargase, li hi enzima li tkisser l-asparagine, komponent importanti tal-proteini li mingħajrha, iċ-ċelluli ma jistgħux jgħixu.

a 3-month study in mice with pegaspargase at doses up to 500 u/kg intraperitoneal or intramuscular resulted in slight hepatocellular changes only at the highest intraperitoneal dose.
studju, li dam 3 xhur, dwar pegaspargase, f'dożi sa 500 u/kg ġol-peritonew jew ġol-muskoli fil- ġrieden, irriżulta f'bidliet epatoċellulari żgħar biss fl-ogħla doża ġol-peritonew.

no reproduction studies in animals with pegaspargase were performed but studies in animals with l-asparaginase have shown teratogenicity (see section 5.3).
ma sarux studji dwar ir-riproduzzjoni b'pegaspargase fl-annimali, iżda studji fl-annimali b'l-asparaginase urew teratoġeniċità (ara sezzjoni 5.3).