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riavviate.
reboot.
Letzte Aktualisierung: 2018-02-13
Nutzungshäufigkeit: 1
Qualität:
attività riavviate
task restarted
Letzte Aktualisierung: 2007-10-31
Nutzungshäufigkeit: 3
Qualität:
riavviate il dispositivo
alzheimer’s disease (ad), the most common neurodegenerative disorder, is the leading cause of dementia. neuritic plaque, one of the major characteristics of ad neuropathology, mainly consists of amyloid β (aβ) protein. aβ is derived from amyloid precursor protein (app) by sequential cleavages of β- and γ-secretase. although app upregulation can promote ad pathogenesis by facilitating aβ production, growing evidence indicates that aberrant post-translational modifications and trafficking of app play a pivotal role in ad pathogenesis by dysregulating app processing and aβ generation. in this report, we reviewed the current knowledge of app modifications and trafficking as well as their role in app processing. more importantly, we discussed the effect of aberrant app modifications and trafficking on aβ generation and the underlying mechanisms, which may provide novel strategies for drug development in ad
Letzte Aktualisierung: 2017-10-08
Nutzungshäufigkeit: 1
Qualität:
Referenz:
riavviate il computer.
reboot your computer.
Letzte Aktualisierung: 2018-02-13
Nutzungshäufigkeit: 2
Qualität:
Referenz:
dopo l'installazione, riavviate l'applicazione.
after the installation proceed with launching the application.
Letzte Aktualisierung: 2018-02-13
Nutzungshäufigkeit: 1
Qualität:
Referenz:
verranno riavviate durante l'installazione remota
will be restarted during the remote installation
Letzte Aktualisierung: 2017-01-22
Nutzungshäufigkeit: 21
Qualität:
Referenz:
server riavviato
server restarted
Letzte Aktualisierung: 2006-11-02
Nutzungshäufigkeit: 13
Qualität:
Referenz: