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medal (multinational etoricoxib and diclofenac arthritis long- term) programmet
multinational etoricoxib and diclofenac arthritis long-term (medal) program the medal program was a prospectively designed cardiovascular (cv) safety outcomes program of pooled data from three randomized, double-blind active comparator controlled trials, the medal study, edge ii and edge.
points to consider on clinical investigation of medicinal products for treatment of rheumatoid arthritis.
note for guidance on clinical investigation of medical products cpmp blood product working party in the treatment of panic disorder
patienter med olika subtyper av psoriasisartrit inkluderades i studierna, såsom polyartikulär artrit utan tecken på reumatiska noduli, spondylit med perifer artrit, asymmetrisk perifer artrit, patienter med påverkan på distala interfalangleder eller arthritis mutilans.
patients with each subtype of psa were enrolled in these studies, including polyarticular arthritis with no evidence of rheumatoid nodules, spondylitis with peripheral arthritis, asymmetric peripheral arthritis, distal interphalangeal involvement and arthritis mutilans.
det kliniska svaret uttrycktes som den procentuella andelen av patienterna som uppnår acr-svar 20, 50 och 70 och procentandelar med förbättring av psoriatic arthritis response criteria (psarc).
clinical responses were expressed as percentages of patients achieving the acr 20, 50, and 70 response and percentages with improvement in psoriatic arthritis response criteria (psarc).
(1) distalt interfalangealt (dip) engagemang; (2) polyartikulär artrit (frånvaro av reumatoida knölar och närvaro av psoriasis); (3) arthritis mutilans; (4) asymmetrisk psoriasisartrit; eller (5) spondylitliknande ankylos.
(1) distal 98 interphalangeal (dip) involvement; (2) polyarticular arthritis (absence of rheumatoid nodules and presence of psoriasis); (3) arthritis mutilans; (4) asymmetric psoriatic arthritis; or (5) spondylitis-like ankylosis.