Sie suchten nach: hydroxylering (Schwedisch - Englisch)

hydroxylering
hydroxylation

ytterligare hydroxylering sker innan eliminering.
further hydroxylation occurs prior to elimination.

metabolismen i katt sker via hydroxylering i levern.
biotransformations in the cat occur by hydroxylation in the liver.

36 därefter genomgår hydroxylering till flera metaboliter.
the major metabolic pathway is deboronation to form two deboronated metabolites that subsequently undergo hydroxylation to several metabolites.

huvudsaklig metabolism hos hunden inkluderar hydroxylering, glukuronsyrakonjugation och
major biotransformations in the dog include hydroxylation, glucuronic acid conjugation and

doxazosin metboliseras huvudsakligen genom o- demetylering och hydroxylering.
doxazosin is primarily metabolised by o-demethylation and hydroxylation.

in vitro är hydroxylering av brivaracetam primärt medierad av cyp2c19.
in vitro, the hydroxylation of brivaracetam is mediated primarily by cyp2c19.

pioglitazon genomgår omfattande levermetabolism genom hydroxylering av alifatiska metylengrupper.
pioglitazone undergoes extensive hepatic metabolism by hydroxylation of aliphatic methylene groups.

metabolism doxazosin metaboliseras främst genom o- demetylering och hydroxylering.
doxazosin is primarily metabolised by o-demethylation and hydroxylation.

celecoxib metaboliseras i levern via hydroxylering, oxidation och i viss mån glukuronidering.
celecoxib is metabolised in the liver by hydroxylation, oxidation and some glucuronidation.

pioglitazon metaboliseras i stor utsträckning i levern genom hydroxylering av alifatiska metylengrupper.
pioglitazone undergoes extensive hepatic metabolism by hydroxylation of aliphatic methylene groups.

metabolism pioglitazon metaboliseras i stor utsträckning via levern genom hydroxylering av alifatiska metylengrupper.
metabolism pioglitazone undergoes extensive hepatic metabolism by hydroxylation of aliphatic methylene groups.

sirolimus metaboliseras i stor utsträckning genom o-demetylering och/eller hydroxylering.
sirolimus is extensively metabolised by o-demethylation and/or hydroxylation.

huvudsaklig metabolism hos hunden inkluderar hydroxylering, glukuronsyrakonjugation och n- metylering i levern.
major biotransformations in the dog include hydroxylation, glucuronic acid conjugation and n- methylation in the liver.

metabolismen sker huvudsakligen genom n-demetylering och hydroxylering följt av konjugering med sulfat och glukuronsyra.
the major routes of metabolism are n-demethylation and hydroxylation, followed by conjugation with sulphate and glucuronic acid.

de huvudsakliga metaboliterna hos människa uppkommer genom hydroxylering av isopropylsidokedjan, antingen på metinkol eller på någon av metylgrupperna.
the main metabolites found in humans result from hydroxylation of the isopropyl side-chain, either on the methine carbon, or one of the methyl groups; activity of the main metabolites is about 5– 6 and 3 times less potent than nateglinide, respectively.

Även om micafungin är substrat för cyp3a in vitro, är hydroxylering genom cyp3a inte någon huvudsaklig nedbrytningsväg för micafungin in vivo.
even though micafungin is a substrate for cyp3a in vitro, hydroxylation by cyp3a is not a major pathway for micafungin metabolism in vivo.

därefter metaboliseras amfenak i hög grad till mer polära metaboliter genom hydroxylering av den aromatiska ringen, vilket leder till bildning av glukuronidkonjugat.
subsequently, amfenac undergoes extensive metabolism to more polar metabolites involving hydroxylation of the aromatic ring leading to glucuronide conjugate formation.

aripiprazol metaboliseras i stor utsträckning i levern primärt genom tre metaboliseringsvägar: dehydrogenering, hydroxylering och n-dealkylering.
aripiprazole is extensively metabolised by the liver primarily by three biotransformation pathways: dehydrogenation, hydroxylation, and n-dealkylation.

kalcitriol är d-vitaminets aktiva metabolit medan alfakalcidol är en kalcitriolanalog som kräver 25-hydroxylering i kroppen för att aktiveras.
as well as being a major source of morbidity fractures due to osteoporosis, particularly hip fractures, are costly in financial terms to society (cooper, 1993; barlow, 1994).