Sie suchten nach: antagonists (Spanisch - Englisch)

they are true antagonists, so to speak.
they are true antagonists, so to speak.

agonists and antagonists "compete" for the same binding site on the receptor.
agonists and antagonists "compete" for the same binding site on the receptor.

the second form of "non-competitive antagonists" act at an allosteric site.
the second form of "non-competitive antagonists" act at an allosteric site.

the term was created to distinguish fully inactive antagonists from weak partial agonists or inverse agonists.
the term was created to distinguish fully inactive antagonists from weak partial agonists or inverse agonists.

antagonists mediate their effects through receptor interactions by preventing agonist-induced responses.
antagonists mediate their effects through receptor interactions by preventing agonist-induced responses.

the bound antagonists may prevent conformational changes in the receptor required for receptor activation after the agonist binds.
the bound antagonists may prevent conformational changes in the receptor required for receptor activation after the agonist binds.

many drugs previously classified as antagonists are now beginning to be reclassified as inverse agonists because of the discovery of constitutive active receptors.
many drugs previously classified as antagonists are now beginning to be reclassified as inverse agonists because of the discovery of constitutive active receptors.

often (though not always) these antagonists possess a very similar chemical structure to that of the agonist.
often (though not always) these antagonists possess a very similar chemical structure to that of the agonist.

===silent antagonists===silent antagonists are competitive receptor antagonists that have zero intrinsic activity for activating a receptor.
===silent antagonists===silent antagonists are competitive receptor antagonists that have zero intrinsic activity for activating a receptor.

in addition, it has been suggested that partial agonism prevents the adaptive regulatory mechanisms that frequently develop after repeated exposure to potent full agonists or antagonists.
in addition, it has been suggested that partial agonism prevents the adaptive regulatory mechanisms that frequently develop after repeated exposure to potent full agonists or antagonists.

in addition, antagonists may interact at unique binding sites not normally involved in the biological regulation of the receptor's activity to exert their effects.
in addition, antagonists may interact at unique binding sites not normally involved in the biological regulation of the receptor's activity to exert their effects.

===uncompetitive===uncompetitive antagonists differ from non-competitive antagonists in that they require receptor activation by an agonist before they can bind to a separate allosteric binding site.
===uncompetitive===uncompetitive antagonists differ from non-competitive antagonists in that they require receptor activation by an agonist before they can bind to a separate allosteric binding site.

in functional assays of non-competitive antagonists, depression of the maximal response of agonist dose-response curves, and in some cases, rightward shifts, is produced.
in functional assays of non-competitive antagonists, depression of the maximal response of agonist dose-response curves, and in some cases, rightward shifts, is produced.

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"","","cabrera garcía, ernesto","","","una tipología del realismo político: aproximación desde el análisis conceptual","","","","","","signos filosóficos","","","","","","","","","1665-1324"," http://www.scielo.org.mx/scielo.php?script=sci_arttext&pid=s1665-13242014000100005&nrm=iso","16","2014","125-155","scielomx",